Tromboelastography in the evaluation of coagulation disorders in patients with sepsis

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dc.contributor.authorKiliç Y.
dc.contributor.authorTopçu I.
dc.contributor.authorBambal H.
dc.contributor.authorÇivi M.
dc.date.accessioned2024-07-22T08:16:21Z
dc.date.available2024-07-22T08:16:21Z
dc.date.issued2014
dc.description.abstractAim: Unbalanced hemostasis and disseminated intravenous coagulopathy serve as key participants in organ dysfunction and disability. In this study we evaluated the coagulation profiles of patients diagnosed with systemic inflammatory syndrome (SIRS)-sepsis and multiple organ dysfunction syndrome. We also researched coagulation in sepsis by comparing thromboelastography (TEG) data with those of nonsepsis patients to determine the usefulness of the TEG device. Materials and methods: Data were collected from 55 anesthesiology and surgery intensive care unit (ICU) patients: 21 with SIRS-sepsis (Group S) and 34 patients without SIRS-sepsis (Group C). Blood samples were taken upon admission to the ICU (t1) and on day 3 of the ICU stay (t2). TEG data (R = reaction time, K = coagulation time, α = alpha angle, and MA = maximum amplitude) were recorded. TEG parameters were compared with routine coagulation and hemogram studies. Results: Te mean R value in Group C was higher than that of Group S at both t1 and t2. Group S had a significantly lower K value and higher alpha angle at t1 compared to Group C (P < 0.05). Conclusion: Hypercoagulability was observed in SIRS-sepsis patients in the ICU, as measured with TEG. We believe that TEG will be a useful tool in the evaluation of coagulation disorders developing in septic critically ill patients. © TÜBİTAK.
dc.identifier.DOI-ID10.3906/sag-1210-99
dc.identifier.issn13000144
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16833
dc.language.isoEnglish
dc.rightsAll Open Access; Bronze Open Access
dc.subjectBlood Pressure
dc.subjectCalcitonin
dc.subjectCase-Control Studies
dc.subjectFemale
dc.subjectHematocrit
dc.subjectHemoglobins
dc.subjectHumans
dc.subjectIntensive Care Units
dc.subjectInternational Normalized Ratio
dc.subjectLeukocyte Count
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMultiple Organ Failure
dc.subjectOxygen
dc.subjectPartial Thromboplastin Time
dc.subjectPlatelet Count
dc.subjectProspective Studies
dc.subjectProtein Precursors
dc.subjectProthrombin Time
dc.subjectSepsis
dc.subjectSystole
dc.subjectThrombelastography
dc.subjectThrombophilia
dc.subjectcalcitonin
dc.subjecthemoglobin
dc.subjectoxygen
dc.subjectprocalcitonin
dc.subjectprotein precursor
dc.subjectadult
dc.subjectarticle
dc.subjectblood clotting disorder
dc.subjectcontrolled study
dc.subjectfemale
dc.subjecthuman
dc.subjecthypercoagulability
dc.subjectincidence
dc.subjectintensive care unit
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmiddle aged
dc.subjectmortality
dc.subjectmultiple organ failure
dc.subjectpartial thromboplastin time
dc.subjectprothrombin time
dc.subjectsepsis
dc.subjectsystemic inflammatory response syndrome
dc.subjectthromboelastography
dc.subjectblood
dc.subjectblood pressure
dc.subjectcase control study
dc.subjecthematocrit
dc.subjectinternational normalized ratio
dc.subjectleukocyte count
dc.subjectprospective study
dc.subjectsystole
dc.subjectthrombocyte count
dc.subjectthrombophilia
dc.titleTromboelastography in the evaluation of coagulation disorders in patients with sepsis
dc.typeArticle

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