Efficacy of 5% imiquimod cream in a patient with classic kaposi sarcoma

Gündüz K.; Günay Ü.; Inanir I.; Gençoǧlan G.; Temiz P.

Efficacy of 5% imiquimod cream in a patient with classic kaposi sarcoma

Date

2012

Authors

Abstract

Background: The classic Kaposi sarcoma is most common in the Mediterranean po-pulation over 50 years of age and presents with reddish-brown papules and nodules particularly on the lower limbs. Treatment depends on the clinical presentation and extension of lesions. Imiquimod is as an immune response modifier with antiangio-genic activity. Main observations: We present a 74-year-old man with classic Kaposi sarcoma who had multiple, small, violaceous papules and nodules on the trunk and extremities with a history of 14 years. He complained particularly from plantar hyperkeratotic painful nodules. Treatment with imiquimod 5% cream under occlusion resulted with almost complete regression within 12 weeks. No local or systemic side effects were observed. Conclusions: Topical imiquimod was a safe and effective therapy in our patient with classic Kaposi sarcoma.