Long-term albendazole treatment in one case of alveolar echinococcosis: Case report
No Thumbnail Available
Date
2003
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Aims: Curative therapy of alveolar echinococcosis is total surgical removal of the infected tissue and concomitant chemotherapy. However, this curative resection can be done on a limited number of patients, for the remaining ones various palliative procedures can be performed. Method: In this article it is aimed to present the result of long-term albendazole treatment in patient who had a palliative hepatojejunostomy for obstructive jaundice due to unresectable alveolar echinococcosis. Results: Systemic albendazole treatment was initiated in this patient after palliative hepatojejunostomy procedure. During follow up there was no abnormality in blood chemistry and a considerable regression in size of the lesion was found in postoperative month 24. Residual hepatic lesion was histopathologically documented and showed apparently non-viable parasitic cysts by biopsy. These findings suggest the long-term albendazole therapy being parasitocidal. Conclusions: Palliative or mass reduction surgery combined with long-term albendazole therapy is the standard therapy for advanced disease, especially when curative resection might result in significant morbidity and mortality.
Description
Keywords
Adult , Albendazole , Anthelmintics , Digestive System Surgical Procedures , Echinococcosis, Hepatic , Female , Follow-Up Studies , Humans , Time Factors , Tomography, X-Ray Computed , Treatment Outcome , albendazole , adult , article , blood chemistry , case report , female , hepatojejunostomy , histopathology , human , liver hydatid cyst , long term care , palliative therapy , remission