Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data

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dc.contributor.authorOnay Z.R.
dc.contributor.authorEyüboğlu T.Ş.
dc.contributor.authorAslan A.T.
dc.contributor.authorGürsoy T.R.
dc.contributor.authorYalçın E.
dc.contributor.authorKiper N.
dc.contributor.authorEmiralioğlu N.
dc.contributor.authorŞen H.S.
dc.contributor.authorŞen V.
dc.contributor.authorÜnal G.
dc.contributor.authorYılmaz A.İ.
dc.contributor.authorKılınç A.A.
dc.contributor.authorÇokuğraş H.
dc.contributor.authorBaşkan A.K.
dc.contributor.authorYazan H.
dc.contributor.authorÇollak A.
dc.contributor.authorUzuner S.
dc.contributor.authorŞasihüseyinoğlu A.Ş.
dc.contributor.authorÖzcan D.
dc.contributor.authorAltıntaş D.U.
dc.contributor.authorÖztürk G.K.
dc.contributor.authorDemir E.
dc.contributor.authorBingöl A.
dc.contributor.authorBaşaran E.
dc.contributor.authorÇekiç Ş.
dc.contributor.authorSapan N.
dc.contributor.authorIrmak İ.
dc.contributor.authorDamadoğlu E.
dc.contributor.authorTuğcu G.D.
dc.contributor.authorPolat S.E.
dc.contributor.authorÖzdemir A.
dc.contributor.authorHarmancı K.
dc.contributor.authorKılıç G.
dc.contributor.authorHangül M.
dc.contributor.authorKöse M.
dc.contributor.authorTamay Z.
dc.contributor.authorYüksel H.
dc.contributor.authorÖzcan G.
dc.contributor.authorTopal E.
dc.contributor.authorCan D.
dc.contributor.authorKorkmaz P.
dc.contributor.authorÇaltepe G.
dc.contributor.authorKılıç M.
dc.contributor.authorÖzdoğan Ş.
dc.contributor.authorÇakır E.
dc.contributor.authorÇobanoğlu N.
dc.contributor.authorPekcan S.
dc.contributor.authorCinel G.
dc.contributor.authorÖzçelik U.
dc.contributor.authorDoğru D.
dc.date.accessioned2024-07-22T08:03:30Z
dc.date.available2024-07-22T08:03:30Z
dc.date.issued2023
dc.description.abstractBackground. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral. © 2023, Turkish National Pediatric Society. All rights reserved.
dc.identifier.DOI-ID10.24953/turkjped.2021.4930
dc.identifier.issn00414301
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12309
dc.language.isoEnglish
dc.publisherTurkish National Pediatric Society
dc.rightsAll Open Access; Gold Open Access
dc.subjectCystic Fibrosis
dc.subjectForced Expiratory Volume
dc.subjectHumans
dc.subjectLung
dc.subjectLung Transplantation
dc.subjectReferral and Consultation
dc.subjectRoutinely Collected Health Data
dc.subjectazithromycin
dc.subjectbronchodilating agent
dc.subjectmannitol
dc.subjectproton pump inhibitor
dc.subjectursodeoxycholic acid
dc.subjectAchromobacter
dc.subjectadolescent
dc.subjectadult
dc.subjectallergic bronchopulmonary aspergillosis
dc.subjectarterial embolization
dc.subjectarterial gas
dc.subjectArticle
dc.subjectartificial ventilation
dc.subjectatypical mycobacteriosis
dc.subjectatypical Mycobacterium
dc.subjectbody mass
dc.subjectBurkholderia cepacia
dc.subjectBurkholderia cepacia infection
dc.subjectchronic obstructive lung disease
dc.subjectclinical feature
dc.subjectcontrolled study
dc.subjectcystic fibrosis
dc.subjectechocardiography
dc.subjectenzyme replacement
dc.subjectfemale
dc.subjectforced expiratory volume
dc.subjectforced vital capacity
dc.subjectgene mutation
dc.subjectHaemophilus influenzae
dc.subjectHaemophilus influenzae infection
dc.subjecthemoptysis
dc.subjecthuman
dc.subjectintensive care unit
dc.subjectlength of stay
dc.subjectliver disease
dc.subjectlung function
dc.subjectlung function test
dc.subjectlung transplantation
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmalnutrition
dc.subjectmethicillin resistant Staphylococcus aureus
dc.subjectnonhuman
dc.subjectnoninvasive ventilation
dc.subjectosteoporosis
dc.subjectpositive end expiratory pressure ventilation
dc.subjectprophylaxis
dc.subjectPseudomonas aeruginosa
dc.subjectPseudomonas infection
dc.subjectspirometry
dc.subjectStaphylococcus aureus
dc.subjectStaphylococcus aureus infection
dc.subjectStenotrophomonas maltophilia
dc.subjectcomplication
dc.subjectcystic fibrosis
dc.subjectlung
dc.subjectpatient referral
dc.subjectroutinely collected health data
dc.titleClinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data
dc.typeArticle

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