The imbalance of enzymatic antioxidants in cholesteatoma

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dc.contributor.authorEskiizmir G.
dc.contributor.authorYuceturk A.V.
dc.contributor.authorOnur E.
dc.contributor.authorVar A.
dc.contributor.authorTemiz P.
dc.date.accessioned2024-07-22T08:21:25Z
dc.date.available2024-07-22T08:21:25Z
dc.date.issued2009
dc.description.abstractConclusion. Depletion of enzymatic antioxidants was observed in cholesteatoma. However, a relationship between activity of enzymatic antioxidants and the extent of bone erosion was not found. Objectives. To measure the level of major enzymatic antioxidants in cholesteatoma, and to investigate the relationship between the level of enzymatic antioxidants and the extent of bone erosion. Patients and methods. The cholesteatoma and skin samples were obtained during otologic surgeries. All cases were grouped according to the number of bone erosion sites. Samples were examined biochemically and the levels of enzymatic antioxidants were measured. The results were analyzed statistically. Results. Thirteen patients were included in the study. The mean level of superoxide dismutase in cholesteatoma and skin was 45.87 U/mg and 71.04 U/mg, respectively. When the catalase level was evaluated, the mean level was 5.04 U/g in cholesteatoma and 11.62 U/g in skin. The mean level of glutathione peroxidase in cholesteatoma and skin was 12.13 IU/g and 236.74 IU/g, respectively. All the results of cholesteatoma and skin samples were compared through non-parametric tests and statistically significant differences were found. However, a statistically significant difference between the levels of enzymatic antioxidants and the extent of bone erosion was not observed.
dc.identifier.DOI-ID10.3109/00016480802593489
dc.identifier.issn16512553
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18592
dc.language.isoEnglish
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAntioxidants
dc.subjectCatalase
dc.subjectCholesteatoma, Middle Ear
dc.subjectEar Canal
dc.subjectEar Ossicles
dc.subjectFemale
dc.subjectGlutathione Peroxidase
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectReference Values
dc.subjectSemicircular Canals
dc.subjectSkin
dc.subjectStatistics, Nonparametric
dc.subjectSuperoxide Dismutase
dc.subjectTemporal Bone
dc.subjectYoung Adult
dc.subjectcatalase
dc.subjectglutathione peroxidase
dc.subjectsuperoxide dismutase
dc.subjectadolescent
dc.subjectadult
dc.subjectarticle
dc.subjectbone erosion
dc.subjectcholesteatoma
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectenzyme activity
dc.subjectfemale
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmale
dc.subjectpriority journal
dc.subjectskin
dc.subjecttissue level
dc.titleThe imbalance of enzymatic antioxidants in cholesteatoma
dc.typeArticle

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