Cyclic lymphocytic vasculitis associated with chronic lymphocytic leukemia
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Date
2004
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Abstract
Lymphocytic cutaneous vasculitis associated with a haematological malignancy has rarely been reported. Here, we describe a 61 year-old woman with chronic lymphocytic leukemia (CLL) who presented with cutaneous lesions on both hands. These lesions improved after all combination chemotherapy courses and recurred before each course. Repetitive skin biopsies revealed lymphocytic vasculitis. After 7 courses of chemotherapy, she had a complete remission. Skin lesions disappeared and did not recur. The cyclic pattern of lymphocytic vasculitis and its relation with CLL disease activity are interesting clinical features in this case. © 2004 Taylor & Francis Ltd.
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Keywords
Antineoplastic Combined Chemotherapy Protocols , Female , Humans , Leukemia, Lymphocytic, Chronic , Middle Aged , Paraneoplastic Syndromes , Remission Induction , Skin Diseases, Vascular , T-Lymphocytes , Vasculitis , cyclophosphamide , prednisone , steroid , vincristine , adult , article , cancer combination chemotherapy , cancer infiltration , case report , chronic lymphatic leukemia , clinical feature , differential diagnosis , disease association , female , granuloma annulare , hand disease , hematologic disease , human , human tissue , immunofluorescence test , immunohistochemistry , laboratory test , physical examination , priority journal , recurrent disease , remission , skin biopsy , skin disease , skin lymphocytic vasculitis , vasculitis