The effect of combination of sevoflurane and desflurane with fentanyl and remifentanil on different recovery scores in outpatient anesthesia; [Günübirlik Anestezide Sevofluran Veya Desfluran Ile Birlikte Fentanil ve Remifentanil Kombinasyonunun Farkli Derlenme Skorlari Ile Karşilaştirilmasi]

Tezcan Keleş G.; Toprak V.; Ekici Z.; Tok D.

The effect of combination of sevoflurane and desflurane with fentanyl and remifentanil on different recovery scores in outpatient anesthesia; [Günübirlik Anestezide Sevofluran Veya Desfluran Ile Birlikte Fentanil ve Remifentanil Kombinasyonunun Farkli Derlenme Skorlari Ile Karşilaştirilmasi]

Date

2005

Authors

Abstract

We aim to compare sevoflurane and desflurane with fentanil and remifentanil in the operating room (OR-Phase-1) and post-anaesthesia care unit (PACU-Phase-2) by using Fast-Tract-Criteria (FTC) and Aldrete Criteria (AC) for ambulatory anesthesia. After obtaining approval from the Faculty Ethics Committee, 80 ASA I-II patients, aged 18-60 were randomly divided into four groups (n=20). Following standard anaesthesia induction, Group (S+F) received 1-3 % sevoflurane + 2 μg kg-1h-1 fentanyl, Group (S+R) received 1-3% sevoflurane + 0.25 μg kg-1h-1 remifentanil, Group (D+F) received 2-5 % desflurane + 2 μg kg-1h-1 fentanyl and Group (D+R) received 2-5% desflurane + 0.25 μg kg-1h-1 remifentanil in 60% N2O for anaesthesia management. Fifteen minutes before the end of the surgery, standard analgesic and anti-emetic medications were applied to all patients. Extubation times were recorded, FTC and AC were evaluated in the OR at the 5th and 10th minutes following extubation and in PACU at the 5th, 15th and 25th minutes. Pain and emesis were evaluated in the PACU. P<0.05 was considered significant. In phase 1 at the 10th min; Group (D+R) had a higher AC score than group (S+F) (p<0.05), in phase 2 at the 5th min; Group (D+R) had higher FTC and AC scores than the other groups (p<0.01 and p<0.05). In phase 2 at the 15th minute, Group (S+F) had a lower AC score than the other groups (p<0.05). In all patients, targeted discharge points were achieved at the 25th minute in PACU. In conclusion, both FTC and AC were applied easily in Phase 1 and Phase 2 to the four groups. The desflurane and remifentanil combination seems to be the most suitable for outpatient anesthesia.