Delayed renal excretion of methotrexate after a severe anaphylactic reaction to methotrexate in a child with osteosarcoma

Simple item page
dc.contributor.authorOzguven A.A.
dc.contributor.authorUysal K.
dc.contributor.authorGunes D.
dc.contributor.authorKoroglu T.
dc.contributor.authorGurcu O.
dc.contributor.authorOlgun N.
dc.date.accessioned2024-07-22T08:21:37Z
dc.date.available2024-07-22T08:21:37Z
dc.date.issued2009
dc.description.abstractAlthough methotrexate is an agent widely used in the practice of pediatric oncology, allergic reactions to methotrexate are most unusual. Most of these reactions typically occur after repeated administration. Here, we report a severe anaphylactoid reaction to the first dose of high-dose methotrexate infusion in a child with osteosarcoma who has also experienced a delayed excretion of methotrexate. Clinicians must be aware of the possibility of a systemic, near-fatal anaphylactic reactions with methotrexate and patients who experience severe anaphylactic reactions should be followed carefully because of the possibility of delayed methotrexate excretion. © 2009 Lippincott Williams & Wilkins Inc.
dc.identifier.DOI-ID10.1097/MPH.0b013e318199388c
dc.identifier.issn15363678
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18693
dc.language.isoEnglish
dc.subjectAdolescent
dc.subjectAnaphylaxis
dc.subjectAntimetabolites, Antineoplastic
dc.subjectBone Neoplasms
dc.subjectFemale
dc.subjectHumans
dc.subjectMethotrexate
dc.subjectOsteosarcoma
dc.subjectSeverity of Illness Index
dc.subjectadrenalin
dc.subjectcarboplatin
dc.subjectcisplatin
dc.subjectcreatinine
dc.subjectdexamethasone
dc.subjectdiphenhydramine
dc.subjectdobutamine
dc.subjectdopamine
dc.subjectdoxorubicin
dc.subjectetoposide
dc.subjectfolinic acid
dc.subjectgranisetron
dc.subjectifosfamide
dc.subjectmethotrexate
dc.subjectantineoplastic antimetabolite
dc.subjectmethotrexate
dc.subjectadolescent
dc.subjectanaphylaxis
dc.subjectarticle
dc.subjectcase report
dc.subjectclinical feature
dc.subjectcreatinine blood level
dc.subjectdrug excretion
dc.subjectdrug megadose
dc.subjectdrug substitution
dc.subjectdrug withdrawal
dc.subjectface edema
dc.subjectfemale
dc.subjectfever
dc.subjectflushing
dc.subjecthuman
dc.subjecthypotension
dc.subjectkidney failure
dc.subjectnephrotoxicity
dc.subjectosteosarcoma
dc.subjectpriority journal
dc.subjectside effect
dc.subjecttachycardia
dc.subjecttremor
dc.subjecturinary excretion
dc.subjecturticaria
dc.subjectvomiting
dc.subjectanaphylaxis
dc.subjectbone tumor
dc.subjectchemically induced disorder
dc.subjecthospitalization
dc.subjecturine
dc.titleDelayed renal excretion of methotrexate after a severe anaphylactic reaction to methotrexate in a child with osteosarcoma
dc.typeArticle

Files

Collections

Scopus Koleksiyonu