Prevalence of toxoplasmosis and genetic characterization of Toxoplasma gondii strains isolated in wild birds of prey and their relation with previously isolated strains from Turkey

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dc.contributor.authorKarakavuk M.
dc.contributor.authorAldemir D.
dc.contributor.authorMercier A.
dc.contributor.authorŞahar E.A.
dc.contributor.authorCan H.
dc.contributor.authorMurat J.-B.
dc.contributor.authorDöndüren Ö.
dc.contributor.authorCan Ş.
dc.contributor.authorÖzdemir H.G.
dc.contributor.authorDöşkaya A.D.
dc.contributor.authorPektaş B.
dc.contributor.authorDardé M.-L.
dc.contributor.authorGürüz A.Y.
dc.contributor.authorDöşkaya M.
dc.date.accessioned2024-07-22T08:09:57Z
dc.date.available2024-07-22T08:09:57Z
dc.date.issued2018
dc.description.abstractToxoplasma gondii is a protozoon parasite that causes congenital toxoplasmosis, as well as other serious clinical presentations, in immune compromised humans. Analyses of the prevalence and genotyping of strains from the definitive host and intermediate hosts will help to understanding the circulation of the different strains and elucidating the role of the genotype (s) in human toxoplasmosis. Turkey has a specific geographic location bridging Africa, Europe, and Asia. We hypothesized that T. gondii strains may have been transferred to Turkey from these continents via migratory birds or vice versa. The present study aimed to assess the prevalence of toxoplasmosis in wild birds of prey of İzmir and Manisa provinces as well as genetically characterize T. gondii strains from these wild birds to show the relation between bird strains and neighboring stray cats as well as human strains previously isolated in Turkey. Tissues obtained from 48 wild birds were investigated for the presence of T. gondii DNA and then bioassayed in mouse. Isolated strains were genotyped using 15 microsatellite markers. The prevalence of T. gondii DNA was found to be 89.6% (n: 43/48) in wild birds. Out of 43 positive samples, a total of 14 strains were genotyped by 15 microsatellite markers. Among them, eight were type II, three were type III and three were mixture of genotypes (two type II/II and one was II/III). These are the first data that showed the presence of T. gondii and types II and III genotypes in wild birds of Turkey. Moreover, Africa 1 was not detected. In addition, cluster analysis showed that T. gondii strains within type II and III lineage have close relation with strains previously isolated from stray cats in İzmir. Further studies are required to isolate more strains from human cases, other intermediate hosts, and water sources to reveal this relation. © 2018 Karakavuk et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.identifier.DOI-ID10.1371/journal.pone.0196159
dc.identifier.issn19326203
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15018
dc.language.isoEnglish
dc.publisherPublic Library of Science
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.subjectAnimals
dc.subjectAnimals, Wild
dc.subjectBirds
dc.subjectDisease Models, Animal
dc.subjectGenetic Variation
dc.subjectGenotype
dc.subjectGeography
dc.subjectMice
dc.subjectMicrosatellite Repeats
dc.subjectMolecular Typing
dc.subjectPhylogeny
dc.subjectToxoplasma
dc.subjectToxoplasmosis, Animal
dc.subjectTurkey
dc.subjectprotozoal DNA
dc.subjectmicrosatellite DNA
dc.subjectAccipiter nisus
dc.subjectanimal tissue
dc.subjectArticle
dc.subjectAthene noctua
dc.subjectbioassay
dc.subjectbird
dc.subjectBubo bubo
dc.subjectBurhinus oedicnemus
dc.subjectButeo buteo
dc.subjectCiconia ciconia
dc.subjectCiconia nigra
dc.subjectcluster analysis
dc.subjectColumba palumbus
dc.subjectcontrolled study
dc.subjectFalco peregrinus
dc.subjectFalco tinnunculus
dc.subjectfalcon
dc.subjectfemale
dc.subjectgenetic analysis
dc.subjectgenetic trait
dc.subjectgenotype
dc.subjecthuman
dc.subjectLarus michahellis michahellis
dc.subjectLuscinia luscinia
dc.subjectmicrosatellite marker
dc.subjectmouse
dc.subjectnonhuman
dc.subjectPelecanus crispus
dc.subjectPhalacrocorax carbo
dc.subjectPhoenicopterus roseus
dc.subjectprevalence
dc.subjectprotozoal genetics
dc.subjectSternula albifrons
dc.subjectstray cat
dc.subjectToxoplasma gondii
dc.subjecttoxoplasmosis
dc.subjectTurkey (republic)
dc.subjectTyto alba
dc.subjectwild animal
dc.subjectanimal
dc.subjectanimal toxoplasmosis
dc.subjectclassification
dc.subjectdisease model
dc.subjectgenetic variation
dc.subjectgenetics
dc.subjectgenotype
dc.subjectgeography
dc.subjectisolation and purification
dc.subjectmolecular typing
dc.subjectparasitology
dc.subjectphylogeny
dc.subjectToxoplasma
dc.subjectturkey (bird)
dc.subjectwild animal
dc.titlePrevalence of toxoplasmosis and genetic characterization of Toxoplasma gondii strains isolated in wild birds of prey and their relation with previously isolated strains from Turkey
dc.typeArticle

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