Beyond lowering LDL cholesterol; [LDL kolesterolü düşürmenin ötesi]

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dc.contributor.authorBayturan O.
dc.contributor.authorÜtük O.
dc.contributor.authorTuzcu E.M.
dc.date.accessioned2024-07-22T08:20:22Z
dc.date.available2024-07-22T08:20:22Z
dc.date.issued2011
dc.description.abstractCompelling evidence from randomized controlled studies demonstrated the crucial role of lowering low-density lipoprotein cholesterol (LDL-C) in the prevention of vascular events. However, not all patients with low LDL-C levels show similar reduction in event rates. The residual risk factors associated with ongoing vascular events despite achieving low LDL-C levels remain to be elucidated. New data suggest that beyond statin therapy, inflammatory mediators, high non-HDL (high-density lipoprotein) cholesterol or apolipoprotein B, small dense LDL-C, type 2 diabetes mellitus, and lifestyle features may have impact on residual vascular risk. In this review, we discussed the significance of identifying these residual risk factors and developing new treatment strategies to further decrease vascular events. The importance of imaging arterial wall to evaluate the effect of various medical therapies has also stated. © 2011 by AVES Yayi{dotless}nci{dotless}li{dotless}k Ltd.
dc.identifier.DOI-ID10.5152/akd.2011.039
dc.identifier.issn13028723
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18126
dc.language.isoTurkish
dc.subjectAtherosclerosis
dc.subjectCardiovascular Diseases
dc.subjectCholesterol, LDL
dc.subjectHumans
dc.subjectHydroxymethylglutaryl-CoA Reductase Inhibitors
dc.subjectHypercholesterolemia
dc.subjectRisk Factors
dc.subjectUltrasonography, Interventional
dc.subjectapolipoprotein B
dc.subjecthigh density lipoprotein cholesterol
dc.subjectlow density lipoprotein cholesterol
dc.subjectartery wall
dc.subjectcardiovascular risk
dc.subjectdiagnostic imaging
dc.subjecthuman
dc.subjectlifestyle
dc.subjectnon insulin dependent diabetes mellitus
dc.subjectreview
dc.subjectrisk reduction
dc.subjecttreatment planning
dc.subjectvascular disease
dc.titleBeyond lowering LDL cholesterol; [LDL kolesterolü düşürmenin ötesi]
dc.typeReview

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