Where does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird's eye view

Simple item page
dc.contributor.authorYilmaz O.
dc.contributor.authorYuksel H.
dc.date.accessioned2024-07-22T08:11:19Z
dc.date.available2024-07-22T08:11:19Z
dc.date.issued2016
dc.description.abstractAirway remodeling is the chronic outcome of inflammation in asthma and a point of intervention between pediatric and adult ages. Pediatric asthma has been of great interest in the efforts to find a valuable time to interrupt remodeling. Various experimental and clinical research have assessed the effect of current therapeutic modalities on airway remodeling in asthma and many new agents are being developed with promising results. The heterogeneity in the results of these studies may lie in the heterogeneity of pathogenesis leading to asthma and remodeling; underlying the need for individualized treatment of the unique pathogenetic characteristics of each child's asthma. The aim of this review is to summarize the evidence about the influence of current and future therapeutic modalities in the concept of inflammation and remodeling in pediatric asthma. Pediatr Pulmonol. 2016;51:1422–1429. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
dc.identifier.DOI-ID10.1002/ppul.23488
dc.identifier.issn87556863
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15597
dc.language.isoEnglish
dc.publisherJohn Wiley and Sons Inc.
dc.subjectAdministration, Inhalation
dc.subjectAdolescent
dc.subjectAdrenal Cortex Hormones
dc.subjectAirway Remodeling
dc.subjectAnti-Asthmatic Agents
dc.subjectAntibodies, Monoclonal, Humanized
dc.subjectAsthma
dc.subjectBronchodilator Agents
dc.subjectCalcium Channel Blockers
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectCytokines
dc.subjectHumans
dc.subjectInfant
dc.subjectInflammation
dc.subjectInterleukin-5
dc.subjectLeukotriene Antagonists
dc.subjectOmalizumab
dc.subjectTumor Necrosis Factor-alpha
dc.subjectVascular Endothelial Growth Factor A
dc.subjectVitamin D
dc.subjectVitamins
dc.subjectbeta adrenergic receptor stimulating agent
dc.subjectcalcitriol
dc.subjectcalcium channel blocking agent
dc.subjectcytokine antibody
dc.subjectdexamethasone
dc.subjectinterleukin 13 antibody
dc.subjectinterleukin 4 antibody
dc.subjectinterleukin 5 antibody
dc.subjectinterleukin 9 antibody
dc.subjectipratropium bromide
dc.subjectmontelukast
dc.subjectomalizumab
dc.subjectplasminogen activator inhibitor 1
dc.subjectreslizumab
dc.subjectsteroid
dc.subjecttiotropium bromide
dc.subjecttumor necrosis factor antibody
dc.subjectunclassified drug
dc.subjectvasculotropin inhibitor
dc.subjectantiasthmatic agent
dc.subjectbronchodilating agent
dc.subjectcorticosteroid
dc.subjectcytokine
dc.subjectinterleukin 5
dc.subjectleukotriene receptor blocking agent
dc.subjectmepolizumab
dc.subjectmonoclonal antibody
dc.subjecttumor necrosis factor
dc.subjectvasculotropin A
dc.subjectvitamin
dc.subjectvitamin D
dc.subjectairway ultrastructure
dc.subjectasthma
dc.subjectclinical effectiveness
dc.subjectdrug efficacy
dc.subjecthuman
dc.subjectinflammation
dc.subjectpathogenesis
dc.subjectpriority journal
dc.subjectReview
dc.subjectsteroid therapy
dc.subjectadolescent
dc.subjectairway remodeling
dc.subjectantagonists and inhibitors
dc.subjectasthma
dc.subjectchild
dc.subjectimmunology
dc.subjectinfant
dc.subjectinflammation
dc.subjectinhalational drug administration
dc.subjectpathophysiology
dc.subjectphysiology
dc.subjectpreschool child
dc.titleWhere does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird's eye view
dc.typeReview

Files

Collections

Scopus Koleksiyonu