Radiologic features of lumbar spine in ochronosis in late stages
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Date
2006
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Abstract
Ochronosis is a rare hereditary disorder of tyrosine metabolism. Severe degenerative arthritis and spondylosis occur in the later stages of this disease. Radiologic examinations may reveal changes considered almost pathognomonic for ochronosis. We present the radiologic features of the lumbar spine in two ochronotic patients who were diagnosed after radiologic examinations in the late stages of the disease. © Clinical Rheumatology 2005.
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Keywords
Disease Progression , Female , Humans , Lumbar Vertebrae , Magnetic Resonance Imaging , Male , Middle Aged , Ochronosis , Osteoporosis , Tomography, X-Ray Computed , homogentisic acid , adult , article , calcification , case report , clinical feature , computer assisted tomography , diffusion weighted imaging , disease severity , external ear , female , genetic disorder , human , image analysis , intervertebral disk , intervertebral disk hernia , limb weakness , low back pain , lumbar disk hernia , lumbar spine , male , nuclear magnetic resonance imaging , ochronosis , osteoarthritis , osteoporosis , priority journal , radiodiagnosis , skin discoloration , spine radiography , spondylosis , urinalysis