Oropharyngeal carriage and penicillin resistance of Neisseria meningitidis in primary school children in Manisa, Turkey

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dc.contributor.authorGazi H.
dc.contributor.authorSurucuoglu S.
dc.contributor.authorOzbakkaloglu B.
dc.contributor.authorAlkcali S.
dc.contributor.authorOzkutuk N.
dc.contributor.authorDegerli K.
dc.contributor.authorKurutepe S.
dc.date.accessioned2024-07-22T08:24:31Z
dc.date.available2024-07-22T08:24:31Z
dc.date.issued2004
dc.description.abstractIntroduction: To determine the oropharyngeal carriage rates and serogroups of Neisseria meningitidis in primary school children in Manisa, Turkey as well as the prevalence and penicillin resistance of AC meningitidis. Materials and Methods: Throat swabs obtained from 1128 children were cultured and recovered organisms were tested by disk diffusion method and the E-test for antimicrobial susceptibilities. Results: The carriage rate of N. meningitidis in our region was 6.2% (71 strains) and the serogroups identified were serogroups A (28.1%), B (22.5%), C (35.2%), D (2.8%) and W-135 (11.2%). Penicillin resistance was found in 16 strains (22.5%), while beta-lactamase activity was found in none. Conclusions: The carriage rate of N. meningitidis and serogroups are similar to the rates reported in other countries. Continued surveillance of meningococci for antimicrobial resistance will allow early detection of changes in susceptibility patterns that might affect recommendations for chemoprophylaxis as well as for treatment.
dc.identifier.issn03044602
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20011
dc.language.isoEnglish
dc.publisherAcademy of Medicine Singapore
dc.subjectantibiotic agent
dc.subjectbeta lactamase
dc.subjectpenicillin G
dc.subjectadolescent
dc.subjectantibiotic prophylaxis
dc.subjectantibiotic resistance
dc.subjectantibiotic sensitivity
dc.subjectarticle
dc.subjectbacterium carrier
dc.subjectbacterium culture
dc.subjectcontrolled study
dc.subjectenzyme activity
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectNeisseria meningitidis
dc.subjectoropharynx
dc.subjectpenicillin resistance
dc.subjectprimary school
dc.subjectschool child
dc.subjectseroprevalence
dc.subjectstrain difference
dc.subjectTurkey (republic)
dc.titleOropharyngeal carriage and penicillin resistance of Neisseria meningitidis in primary school children in Manisa, Turkey
dc.typeArticle

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