Evaluation of species distribution and risk factors of candidemia: A multicenter case-control study
| dc.contributor.author | Yapar, N | |
| dc.contributor.author | Pullukcu, H | |
| dc.contributor.author | Avkan-Oguz, V | |
| dc.contributor.author | Sayin-Kutlu, S | |
| dc.contributor.author | Ertugrul, B | |
| dc.contributor.author | Sacar, S | |
| dc.contributor.author | Cetin, B | |
| dc.contributor.author | Kaya, O | |
| dc.date.accessioned | 2025-04-10T10:36:13Z | |
| dc.date.available | 2025-04-10T10:36:13Z | |
| dc.description.abstract | This study was planned to determine the risk factors of candidemia, and the most common Candida species causing bloodstream infections. A case-control study which included adult patients was conducted over a 1-year period at tertiary-care educational hospitals in Turkey. A total of 83 candidemia episodes were identified during the study period. Candida albicans was the most common species recovered (45.8%) followed by Candida tropicalis (24.1%) Candida parapsilosis (14.5%) and Candida glabrata which was isolated from only four (4.8%) patients. Presence of a urethral catheter (odds ratio [OR] 2.38; 95% confidence interval [CI] 1.09-5.19; P = 0.02), previous use of antibiotics (OR 2.61; 95% CI 1.05-6.46; P = 0.03), RBC transfusions (OR 2.14; 95% CI 1.16-3.94; P = 0.01) and parenteral nutrition (OR 4.44; 95% CI 2.43-8.11; P < 0.01) were found as independent risk factors for candidemia. TPN (Total Parenteral Nutrition) was an independent risk factor for both C. albicans and non-Candida albicans Candida species (P < 0.001). Most of the risk factors were invasive procedures and former medications. We conclude that a great number of candidemia cases are preventable by means of reduction of unnecessary invasive procedures and the use of antimicrobials. | |
| dc.identifier.e-issn | 1460-2709 | |
| dc.identifier.issn | 1369-3786 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/42123 | |
| dc.language.iso | English | |
| dc.title | Evaluation of species distribution and risk factors of candidemia: A multicenter case-control study | |
| dc.type | Article |