Effects of a kefir supplement on symptoms, colonic transit, and bowel satisfaction score in patients with chronic constipation: A pilot study

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dc.contributor.authorTuran I.
dc.contributor.authorDedeli O.
dc.contributor.authorBor S.
dc.contributor.authorIlter T.
dc.date.accessioned2024-07-22T08:17:06Z
dc.date.available2024-07-22T08:17:06Z
dc.date.issued2014
dc.description.abstractBackground/Aims: Although probiotics have been extensively studied in irritable bowel syndrome, data on the impact of probiotics on chronic constipation are scarce. We aimed to evaluate the effects of kefir, which is a probiotic fermented milk product, on the symptoms, colonic transit, and bowel satisfaction scores of patients with chronic constipation. bMaterials and Methods: Twenty consecutive patients with functional constipation according to the Rome II criteria were divided into two groups based on their colon transit studies: 1. The normal transit (NT) group (n=10); and 2. The slow transit (ST) group (n=10). After a baseline period, 500 mL/day of a probiotic kefir beverage was administered to all patients for 4 weeks. Defecation parameters (stool frequency, stool consistency, degree of straining, blaxative consumption) were recorded in diaries daily by the patients. Bowel satisfaction scores were assessed using a visual analog scale. The colon transit study was repeated in the ST group at the end of the study. bResults: At the end of the study, the patients showed an increased stool frequency (p<0.001), improved stool consistency (p=0.014), and decreased laxative consumption (p=0.031). The degree of straining during evacuation showed a tendency to improve after kefir administration; however, this was not statistically significant (p=0.18). A repeat transit study showed an acceleration of colonic transit in the ST group (p=0.013). Bowel satisfaction scores also improved (p<0.001). bConclusion: This pilot study shows that kefir has positive effects on the symptoms of constipation. Our results also suggest that kefir improves bowel satisfaction scores and accelerates colonic transit. Controlled trials are warranted to confirm these findings. © Copyright 2014 by The Turkish Society of Gastroenterology.
dc.identifier.DOI-ID10.5152/tjg.2014.6990
dc.identifier.issn13004948
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16968
dc.language.isoEnglish
dc.publisherTurkish Society of Gastroenterology
dc.subjectAdult
dc.subjectAged
dc.subjectChronic Disease
dc.subjectColon
dc.subjectConstipation
dc.subjectCultured Milk Products
dc.subjectDietary Supplements
dc.subjectFemale
dc.subjectGastrointestinal Transit
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPilot Projects
dc.subjectProbiotics
dc.subjectkefir
dc.subjectlaxative
dc.subjectprobiotic agent
dc.subjectadult
dc.subjectaged
dc.subjectanorectal pressure
dc.subjectArticle
dc.subjectassessment of humans
dc.subjectbowel satisfaction score
dc.subjectclinical article
dc.subjectcomparative study
dc.subjectconstipation
dc.subjectcontrolled study
dc.subjectdefecation habit
dc.subjectdiet supplementation
dc.subjectfeces incontinence
dc.subjectfemale
dc.subjectgastrointestinal transit
dc.subjecthuman
dc.subjectmale
dc.subjectmiddle aged
dc.subjectpilot study
dc.subjectvisual analog scale
dc.subjectchronic disease
dc.subjectclinical trial
dc.subjectcolon
dc.subjectconstipation
dc.subjectdairy product
dc.subjectdiet supplementation
dc.subjectpathophysiology
dc.titleEffects of a kefir supplement on symptoms, colonic transit, and bowel satisfaction score in patients with chronic constipation: A pilot study
dc.typeArticle

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