Does late-onset hypogonadism occur by aging? The evaluation of IIEF, Ams-Q and biochemical parameters; [Yaşlanmayla geç başlayan hipogonadizm oluşuyor mu? IIEF, Ams-Q ve biyokimyasal deǧerlendirilmesi]

Üçer O.; Gümüş B.; Okur M.; Karataş T.C.; Büyüksu C.

Does late-onset hypogonadism occur by aging? The evaluation of IIEF, Ams-Q and biochemical parameters; [Yaşlanmayla geç başlayan hipogonadizm oluşuyor mu? IIEF, Ams-Q ve biyokimyasal deǧerlendirilmesi]

Date

2010

Authors

Publisher

Turkiye Klinikleri

Abstract

Objective: The aim of this study is to investigate whether biochemical (hormonal) hypogonadism occurs by aging and whether AMS-Q (Aging Male Symptoms-Questionnaire) and IIEF (International Index of Erectile Function) forms are adequate in order to evaluate its presence in case it occurs. Material and Methods: A total of 182 males who applied to the outpatient clinics of Urology Department and whose ages were between 45-90 years were included in the study. Those who had diabetes mellitus, hypertension, coronary artery disease, dyslipidemia, any psychiatric disorder and any malignancy were excluded. The patients were classified into three groups (Group 1; 45-54, Group 2; 55-64 and Group 3; over 65 years). All participants were asked to complete IIEF and AMS-Q forms and serum levels of total testosterone, free testosterone, LH, DHEA-S, SHBG and prolactin were measured. Results: Total testosterone and prolactin levels did not change with aging. Although free testosterone, bio-available testosterone and DHEA-S levels decreased with age, it was detected that LH and SHBG levels were increased. While IIEF scores decreased with age, however AMS-Q scores did not change. When subgroups of AMS-Q were taken into consideration, sexual scores increased, and a decrease in somatic and psychological scores was detected. There was a strong relationship between IIEF-EF (erectile function) and AMS-Sexual forms. Conclusion: All of the data indicate that secondary hypogonadism occurs by aging and consequent symptoms (especially sexual ones) can be evaluated with IIEF and AMS-Sexual forms. © 2010 by Türkiye Klinikleri.