Acute generalized exanthematous pustulosis (AGEP) due to exposure to sulfuric acid and bromic acid vapor: A case report

dc.contributor.authorBilaç D.B.
dc.contributor.authorErmertcan A.T.
dc.contributor.authorÖztürkcan S.
dc.contributor.authorŞahin M.T.
dc.contributor.authorTemiz P.
dc.date.accessioned2024-07-22T08:22:24Z
dc.date.available2024-07-22T08:22:24Z
dc.date.issued2008
dc.description.abstractAcute generalized exanthematous pustulosis (AGEP, toxic pustuloderma, pustular drug eruption) is a not uncommon cutaneous reaction pattern that is usually related to drug administration. The eruption is of sudden onset and appears 7-10 days after the medication is started. A 22-year-old male patient who was a student at a chemical faculty attended our outpatient clinic with a complaint of pustular eruption on his face. According to his history, the eruption started with pruritus and erythema on his chin 3 days ago and spread to his face and chest. He explained that he had performed an experiment with sulfuric acid and bromic acid and was exposed to their vapor. His dermatological examination revealed erythema and pustules on his cheeks, on his chin, above his upper lip, and on his eyebrows. He also had a few pustules on his chest. There were no ocular, mucous membrane, or pulmonary symptoms. Histopathological examination of the skin biopsy specimen revealed superficial orthokeratosis, focal subcorneal pustule formation, and perivascular chronic inflammatory cell infiltration in superficial dermis. After administration of systemic antihistamines and wet dressing topically, we observed rapid healing of the lesions. Because there was no systemic drug intake in his history, we were concerned that exposure to sulfuric acid and bromic acid vapor caused AGEP in this patient. We present this rare case to show that the vapor of chemical materials may cause AGEP or other drug eruptions. Copyright © Informa Healthcare.
dc.identifier.DOI-ID10.1080/15569520802060416
dc.identifier.issn15569535
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19067
dc.language.isoEnglish
dc.subjectAccidents, Occupational
dc.subjectAcids, Noncarboxylic
dc.subjectAdult
dc.subjectHumans
dc.subjectHydrobromic Acid
dc.subjectLaboratories
dc.subjectMale
dc.subjectSkin
dc.subjectSkin Diseases, Vesiculobullous
dc.subjectSulfuric Acids
dc.subjectamoxicillin
dc.subjectamoxicillin plus clavulanic acid
dc.subjectantihistaminic agent
dc.subjectbromate
dc.subjectcarbamazepine
dc.subjectclavulanic acid
dc.subjectpristinamycin
dc.subjectspiramycin
dc.subjectsulfuric acid
dc.subjectterbinafine
dc.subjectacute generalized exanthematous pustulosis
dc.subjectadult
dc.subjectarticle
dc.subjectcase report
dc.subjectcell infiltration
dc.subjectcheek
dc.subjectchin
dc.subjectchronic inflammation
dc.subjectdrug eruption
dc.subjecterythema
dc.subjecteyebrow
dc.subjecthistopathology
dc.subjecthuman
dc.subjectkeratosis
dc.subjectlip
dc.subjectmale
dc.subjectoutpatient
dc.subjectpruritus
dc.subjectpustulosis
dc.subjectskin biopsy
dc.subjectskin examination
dc.subjectwound dressing
dc.subjectwound healing
dc.titleAcute generalized exanthematous pustulosis (AGEP) due to exposure to sulfuric acid and bromic acid vapor: A case report
dc.typeArticle

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