Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues
| dc.contributor.author | Emre, S | |
| dc.contributor.author | Yilmaz, Z | |
| dc.contributor.author | Öztürk, F | |
| dc.contributor.author | Emre, MH | |
| dc.date.accessioned | 2025-04-10T10:33:40Z | |
| dc.date.available | 2025-04-10T10:33:40Z | |
| dc.description.abstract | Aim: This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol. To counterbalance caloric intake, we decreased the amount of glucose in the special liquid diet for groups 3 and 4. At the end of 30 days, the animals were sacrificed and samples were kept at -80 degrees C until evaluation. Specimens were investigated by light microscopy for morphology and morphometry. Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group (p < 0.05). This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group (p > 0.05). Alcohol did not cause any significant alteration of rat retinal thickness. Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake. Copyright (C) 2009 S. Karger AG, Basel | |
| dc.identifier.issn | 0030-3747 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/39925 | |
| dc.language.iso | English | |
| dc.title | Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues | |
| dc.type | Article |