Synthesis, radiolabeling and in vitro evaluation of azathioprine loaded magnetic solid lipid nanoparticles

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dc.contributor.authorTürkkani, G
dc.contributor.authorGüngör, B
dc.contributor.authorCetin, O
dc.contributor.authorIçhedef, Ç
dc.contributor.authorParlak, Y
dc.contributor.authorGümüser, FG
dc.contributor.authorBilgin, BES
dc.contributor.authorTeksöz, S
dc.date.accessioned2025-04-10T10:32:31Z
dc.date.available2025-04-10T10:32:31Z
dc.description.abstractIn this study, it is aimed to design a smart drug delivery system for the diagnosis and treatment of cancer cells. Magnetic-solid lipid nanoparticles were synthesized as a drug delivery system and azathioprine (AZA) was loaded into this system. This newly created system was radiolabeled using technetium-99 m with a radiolabeling yield of 90.3%. Drug loading into the SLMNP was found as 86%. The biological behavior of Tc-99m and radiolabeled magnetic solid lipid nanoparticles loaded with azathioprine (Tc-99m-AZA-SLMNP) was investigated in vitro and in vivo.
dc.identifier.e-issn1588-2780
dc.identifier.issn0236-5731
dc.identifier.urihttp://hdl.handle.net/20.500.14701/38906
dc.language.isoEnglish
dc.titleSynthesis, radiolabeling and in vitro evaluation of azathioprine loaded magnetic solid lipid nanoparticles
dc.typeArticle

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