LC–ESI–MS/MS characterization of phytochemical and enzyme inhibitory effects of different solvent extract of Symphytum anatolicum

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dc.contributor.authorSarikurkcu C.
dc.contributor.authorOzer M.S.
dc.contributor.authorTlili N.
dc.date.accessioned2024-07-22T08:08:22Z
dc.date.available2024-07-22T08:08:22Z
dc.date.issued2019
dc.description.abstractSymphytum anatolicum Boiss., is a species belonging to the Boraginaceae family and have been used for its curative effects. This work investigated, for the first time, the bioactive compounds, the antioxidant activities and the enzyme inhibitory effects of Symphytum anatolicum roots extracts using three solvents (methanol, water and ethyl acetate). The LC–ESI–MS/MS was used to identify the individual bioactive compounds. Twenty-three biomolecules were identified in the extracts and rosmarinic acid, verbascoside, caffeic acid, chlorogenic acid and vanillin were the main identified with varied levels depending on the solvent used. Using six different assays, all extracts exhibited important antioxidant activities. Results showed also that the methanol extract exerted better tyrosinase inhibitory activities while ethyl acetate extract showed the best α-amylase inhibition. The obtained results highlighted the importance of S. anatolicum as a natural resource of bioactive compounds and encourage the use of this unexploited species for food additives, pharmaceutical industries, and skincare products. © 2019 Elsevier B.V.
dc.identifier.DOI-ID10.1016/j.indcrop.2019.111666
dc.identifier.issn09266690
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14364
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.subjectBoraginaceae
dc.subjectSymphytum
dc.subjectAdditives
dc.subjectAmylases
dc.subjectAntioxidants
dc.subjectMethanol
dc.subjectOrganic solvents
dc.subjectAlpha-amylase inhibitions
dc.subjectAnti-oxidant activities
dc.subjectBioactive compounds
dc.subjectLC-ESI-MS/MS
dc.subjectPharmaceutical industry
dc.subjectSymphytum anatolicum
dc.subjectTyrosinase
dc.subjectTyrosinase inhibitory activities
dc.subjectantioxidant
dc.subjectchemical compound
dc.subjectdicotyledon
dc.subjectenzyme
dc.subjectenzyme activity
dc.subjectliquid chromatography
dc.subjectmass spectrometry
dc.subjectphysicochemical property
dc.subjectphytochemistry
dc.subjectplant extract
dc.subjectsolvent
dc.subjectSolvent extraction
dc.titleLC–ESI–MS/MS characterization of phytochemical and enzyme inhibitory effects of different solvent extract of Symphytum anatolicum
dc.typeArticle

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