Diagnostic value of perinatal autopsies: Analysis of 486 cases

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dc.contributor.authorNeşe N.
dc.contributor.authorBülbül Y.
dc.date.accessioned2024-07-22T08:09:55Z
dc.date.available2024-07-22T08:09:55Z
dc.date.issued2018
dc.description.abstractAim: Autopsy is a beneficial procedure to determine the cause of death and the frequency of anomalies in perinatal losses. Even in the event of an autopsy not providing any additional information, completion of the procedure confirming the clinical diagnoses gives reassurance to both clinicians and parents. Here we present a 15-year archival study based on findings of perinatal autopsies. Design and methods: Four hundred and eighty-six cases from our archive were reviewed and according to the findings they were divided into three subcategories; (1) miscarriages (MCF); (2) fetuses terminated (FTA) for vital anomalies detected by prenatal ultrasonography; (3) premature or term newborns died within first month of life (neonates: NN). Autopsies were documented and classified according to week/age of cases, anomalies and causes of abortion or death. Results: Two hundred and twenty-six of 486 cases (46.5%) were in MCF group while 227 (46.7%) and 33 (6.8%) were of them in FTA and NN groups, respectively. In FTA group, the most frequent anomaly detected was neural tube defects. In NN group, prematurity related complications were the most common cause of death. The autopsy process was found valuable in 39.7% of all cases. Conclusions: We suggest that autopsy procedure is diagnostically valuable even in situations when there is USG findings that are confirming FTAs or there is no important major fetal or placental anomaly detected in MCFs. © 2018 Walter de Gruyter GmbH, Berlin/Boston.
dc.identifier.DOI-ID10.1515/jpm-2016-0396
dc.identifier.issn03005577
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15002
dc.language.isoEnglish
dc.publisherWalter de Gruyter GmbH
dc.subjectAbortion, Spontaneous
dc.subjectAutopsy
dc.subjectCause of Death
dc.subjectFemale
dc.subjectFetal Death
dc.subjectFetal Diseases
dc.subjectHumans
dc.subjectInfant
dc.subjectInfant Death
dc.subjectInfant, Newborn
dc.subjectInfant, Newborn, Diseases
dc.subjectPregnancy
dc.subjectReproducibility of Results
dc.subjectTurkey
dc.subjectabortion
dc.subjectArticle
dc.subjectautopsy
dc.subjectcause of death
dc.subjectclassification
dc.subjectdiagnostic value
dc.subjectfemale
dc.subjectfetus
dc.subjectfetus disease
dc.subjectfetus echography
dc.subjectfetus malformation
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical history
dc.subjectneural tube defect
dc.subjectnewborn
dc.subjectnewborn death
dc.subjectnewborn disease
dc.subjectperinatal period
dc.subjectprematurity
dc.subjectpriority journal
dc.subjectscoring system
dc.subjectspontaneous abortion
dc.subjectchild death
dc.subjectepidemiology
dc.subjectfetus death
dc.subjectfetus disease
dc.subjectinfant
dc.subjectmortality
dc.subjectnewborn disease
dc.subjectpathology
dc.subjectpregnancy
dc.subjectprocedures
dc.subjectreproducibility
dc.subjectspontaneous abortion
dc.subjectstatistics and numerical data
dc.subjectturkey (bird)
dc.titleDiagnostic value of perinatal autopsies: Analysis of 486 cases
dc.typeArticle

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