Synthesis of 5-fluorouracil dimer containing 2-amino-thiazole group via click reaction; [2-amino-tiyazol grubu içeren 5-florourasil dimerinin klik tepkimesi yoluyla sentezi]

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dc.contributor.authorÖztürkoğlu G.
dc.contributor.authorAy E.
dc.contributor.authorAlp H.
dc.contributor.authorAy K.
dc.date.accessioned2024-07-22T08:06:56Z
dc.date.available2024-07-22T08:06:56Z
dc.date.issued2021
dc.description.abstractSince cancer is one of the leading diseases that cause human deaths in the world, the synthesis of anticancer or new compounds with fewer side effects is important. 5-Fluorouracil (5-FU) is one of the oldest compounds used for chemotherapy. In this study, 1,2,3-triazole bridge containing compound 4, which could have potential anticancer properties, was synthesized via the click reaction from the 5-FU and 2-aminothiazole using the molecular hybridization approach. The structural elucidation of the new compound was carried out using modern spectroscopic methods such as FTIR,1H,13C,19F, COSY, HSQC, HMBC and TOF-MS. © 2021, TUBITAK. All rights reserved.
dc.identifier.DOI-ID10.31202/ecjse.789749
dc.identifier.issn21483736
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13764
dc.language.isoTurkish
dc.publisherTUBITAK
dc.rightsAll Open Access; Gold Open Access
dc.titleSynthesis of 5-fluorouracil dimer containing 2-amino-thiazole group via click reaction; [2-amino-tiyazol grubu içeren 5-florourasil dimerinin klik tepkimesi yoluyla sentezi]
dc.typeArticle

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