Musculoskleletal manifestations of generalized lipodystrophy
No Thumbnail Available
Date
2005
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The lipoatrophic-lipodystrophic syndromes are a heterogeneous group of adipose tissue disorders characterized by selective and progressive loss of fat from various parts of the body. Affected patients have acantosis nigricans, corneal opacities, mental retardation, hirsutism and accelerated growth and maturation. We report the musculoskeletal findings of a case of acquired lipodystrophy with symmetrical involvement of appendicular skeleton. Although more than 500 cases with various types of lipodistrophy have been reported there is little emphasis on the musculoskeletal manifestations. © 2004 Elsevier Ireland Ltd. All rights reserved.