Synthesis and Characterization of Chloralose-Derived Thiosemicarbazones and Semicarbazones and Investigation of Their Antimicrobial Properties

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dc.contributor.authorYetgin, CE
dc.contributor.authorOskay, M
dc.contributor.authorAy, K
dc.date.accessioned2025-04-10T10:30:04Z
dc.date.available2025-04-10T10:30:04Z
dc.description.abstractThiosemicarbazones(7-10)/semicarbazones(11-14) were synthesized in good yields via the condensation of alpha-gluco-, beta-gluco-, galacto-, manno-chloralose derived 1,4-furanodialdoses (1-4) with thiosemicarbazide(5)/semicarbazide(6). The structures of all products were characterized by FTIR, NMR spectroscopic methods and elemental analysis. The compounds have been found to display moderate antimicrobial activity against Gram-positive, Gram-negative bacteria and antifungal activity against a Candida albicans. MIC values of the compounds range from 260 to 1510 mu g/mL.
dc.identifier.e-issn1532-2327
dc.identifier.issn0732-8303
dc.identifier.urihttp://hdl.handle.net/20.500.14701/36710
dc.language.isoEnglish
dc.titleSynthesis and Characterization of Chloralose-Derived Thiosemicarbazones and Semicarbazones and Investigation of Their Antimicrobial Properties
dc.typeArticle

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