Nutritional characteristic of children with inflammatory bowel disease in the nationwide inflammatory bowel disease registry from the Mediterranean region

Simple item page
dc.contributor.authorKuloglu Z.
dc.contributor.authorÇetin F.
dc.contributor.authorUrgancı N.
dc.contributor.authorÖnal Z.
dc.contributor.authorSarı S.
dc.contributor.authorYüksekkaya H.
dc.contributor.authorÇaltepe G.
dc.contributor.authorKutluk G.
dc.contributor.authorDumlupinar E.
dc.contributor.authorAkçam M.
dc.contributor.authorArslan D.
dc.contributor.authorArslan N.
dc.contributor.authorArtan R.
dc.contributor.authorUncuoğlu Aydoğan A.
dc.contributor.authorBalamtekin N.
dc.contributor.authorBaran M.
dc.contributor.authorBaysoy G.
dc.contributor.authorÇakır M.
dc.contributor.authorÇeltik C.
dc.contributor.authorDalgıç B.
dc.contributor.authorDoğan Y.
dc.contributor.authorDurmaz Ö.
dc.contributor.authorEcevit Ç.
dc.contributor.authorEren M.
dc.contributor.authorErdemir G.
dc.contributor.authorGökçe S.
dc.contributor.authorGulerman F.
dc.contributor.authorGürakan F.
dc.contributor.authorHızlı Ş.
dc.contributor.authorÖzbay Hoşnut F.
dc.contributor.authorIşık İ.
dc.contributor.authorKalaycı A.G.
dc.contributor.authorKansu A.
dc.contributor.authorKarabiber H.
dc.contributor.authorKasırga E.
dc.contributor.authorÖzen H.
dc.contributor.authorÖzkan T.
dc.contributor.authorÖztürk Y.
dc.contributor.authorSayar E.
dc.contributor.authorBekem Soylu Ö.
dc.contributor.authorTosun M.S.
dc.contributor.authorTümgör G.
dc.contributor.authorKorkut Uğraş M.
dc.contributor.authorÜnal F.
dc.contributor.authorÜstündağ G.H.
dc.contributor.authorYaman A.
dc.contributor.authorYücel A.
dc.date.accessioned2024-07-22T08:04:17Z
dc.date.available2024-07-22T08:04:17Z
dc.date.issued2022
dc.description.abstractBackground/objectives: We analyzed the nationwide pediatric inflammatory bowel disease (PIBD) registry (1998–2016), to evaluate the nutritional status at the time of diagnosis. Subjects/methods: Nine types of nutritional status by the combination of weight-for-length (<2 years)/body mass index (>2 years) and length/height-for-age with three categories (<−2, −2 to 2, and >2 SD) were described. Malnutrition was defined by WHO criteria. Univariate and multivariate regression analysis was used to identify risk factors for malnutrition. Results: In total, 824 IBD patients (498 Ulcerative colitis (UC); 289 Crohn’s Disease (CD); 37 Indeterminate Colitis (IC); 412 male; the median age 12.5 years) were eligible. The prevalence of eutrophy, wasting/thinness, stunting, overweight, tall stature, concurrent wasting/thinness and stunting, tall stature with overweight, tall stature with wasting/thinness, and short stature with overweight were 67.4%, 14.9%, 6.6%, 3.1%, 3.2%, 3.3%, 1.1%, 0.4%, and 0.1%, respectively. The prevalence of malnutrition was 32.7%, indicating a higher prevalence in CD (p < 0.001). Incidence of overweight was less common in the CD than UC and IC (p < 0.001). Multivariate analysis revealed that age of onset (>10 years), prepubertal stage, severe disease activity, perianal involvement, and high C reactive protein level were independently associated with malnutrition in pediatric IBD. Conclusion: We showed the frequency of nutritional impairment in PIBD. The percentage of overweight subjects was lower than the other studies. The age of onset, disease activity, CRP level, perianal involvement, and pubertal stage were associated with a higher risk for developing malnutrition. Our results also confirmed that CD patients are particularly vulnerable to nutritional impairment. Clinical trial number: ClinicalTrials.gov Identifier: NCT04457518. © 2022, The Author(s), under exclusive licence to Springer Nature Limited.
dc.identifier.DOI-ID10.1038/s41430-022-01094-6
dc.identifier.issn09543007
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12639
dc.language.isoEnglish
dc.publisherSpringer Nature
dc.subjectC reactive protein
dc.subjectanemia
dc.subjectanthropometric parameters
dc.subjectArticle
dc.subjectbody mass
dc.subjectbreast feeding
dc.subjectchild
dc.subjectCrohn disease
dc.subjectcross-sectional study
dc.subjectdisease activity
dc.subjecterythrocyte sedimentation rate
dc.subjectfemale
dc.subjecthuman
dc.subjecthypoalbuminemia
dc.subjectinflammatory bowel disease
dc.subjectleukocytosis
dc.subjectmale
dc.subjectmalnutrition
dc.subjectmulticenter study
dc.subjectnutritional assessment
dc.subjectnutritional status
dc.subjectobesity
dc.subjectobservational study
dc.subjectonset age
dc.subjectpancolitis
dc.subjectpatient selection
dc.subjectrisk factor
dc.subjectshort stature
dc.subjectsocioeconomics
dc.subjectSouthern Europe
dc.subjectstunting
dc.subjecttall stature
dc.subjectthrombocytosis
dc.subjectulcerative colitis
dc.titleNutritional characteristic of children with inflammatory bowel disease in the nationwide inflammatory bowel disease registry from the Mediterranean region
dc.typeArticle

Files

Collections

Scopus Koleksiyonu