Volumetric Mass Transfer Coefficient Measurement in a Stirred Tank Reactor

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dc.contributor.authorInam A.
dc.contributor.authorTaymaz E.R.
dc.contributor.authorUslu M.E.
dc.contributor.authorBinay B.
dc.contributor.authorDeniz I.
dc.date.accessioned2024-07-22T08:05:14Z
dc.date.available2024-07-22T08:05:14Z
dc.date.issued2022
dc.description.abstractA bioreactor is a controlled vessel which provides biological conversions into bioactive components using cells or enzymes. In the aerobic processes, it is important to know oxygen requirements of the cells which may vary during fermentation as a result of microbial activity, aging, substrate depletion and product formation, etc. Here we describe the measurement of volumetric mass transfer coefficient (kLa) in a stirred tank reactor using dynamic method based on unsteady state which is also one of the significant parameter especially in scaling-up. The equipment in the measurement according to dynamic method has low cost compared to steady-state methodology. This method is reliable in the determination of kLa when the gas residence time and probe measuring the oxygen concentration of response time are in specific requirements. © 2021, Springer Science+Business Media, LLC.
dc.identifier.DOI-ID10.1007/7651_2021_415
dc.identifier.issn10643745
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13056
dc.language.isoEnglish
dc.publisherHumana Press Inc.
dc.subjectBioreactors
dc.subjectFermentation
dc.subjectOxygen
dc.subjectoxygen
dc.subjectoxygen
dc.subjectbacterium culture
dc.subjectbiomass distribution
dc.subjectbiomass fermentation
dc.subjectcell density
dc.subjectcell growth
dc.subjectcontrolled study
dc.subjectcost control
dc.subjectEscherichia coli
dc.subjectinoculation
dc.subjectinstrument sterilization
dc.subjectmicrobial biomass
dc.subjectnonhuman
dc.subjectoptical density
dc.subjectoxygen concentration
dc.subjectoxygen consumption rate
dc.subjectreaction duration (chemistry)
dc.subjectreoxygenation
dc.subjectretention time
dc.subjectscale up
dc.subjectvolumetry
dc.subjectbioreactor
dc.subjectfermentation
dc.titleVolumetric Mass Transfer Coefficient Measurement in a Stirred Tank Reactor
dc.typeBook chapter

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