Underestimated role of alcohol at skin disinfection: Lipid dissolving property when used in association with conventional antiseptic agents; [Alkolün cilt dezenfeksiyonunda önemsenmeyen rolü: Klasik antiseptik ajanlarla birlikte kullanıldıǧında lipit çözücü özelliǧi]
No Thumbnail Available
Date
2010
Authors
Journal Title
Journal ISSN
Volume Title
Abstract
Aim: After conventional aqueous disinfectant solutions, it was shown that microorganisms were still protected in hair follicles. We hypothesized that those aqueous disinfectant solutions when used in combination with alcohol may be more effective on the inhibition of recolonization of skin and therefore catheter tip colonization. & Materials and methods: Skin surface samples were taken from epidural catheter insertion sites prior to catheterization, and before and after disinfection with different combinations of povidone-iodine, chlorhexidine, and alcohol. Before catheter removal, cultures were taken once more and tips of the catheters were cultured. & Results: Catheter tip colonization and skin culture results of 10% povidone-iodine + 70% alcohol group were significantly lower than those of other groups after disinfection. & Conclusion: Sequential use of alcohol and povidone-iodine is the most effective combination for limiting re-colonization of skin flora. Contamination of catheters appears to take place at removal or via the spread of these re-colonized bacteria along the catheter tract. © TÜBİTAK.
Description
Keywords
Alcohols , Diagnosis , Disinfectants , Disinfection , Iodine , alcohol , antiinfective agent , chlorhexidine , disinfectant agent , lipid , povidone iodine , Alcohol group , Antiseptic agents , Chlorhexidine , Colonization , Epidural catheterization , Hair follicles , Insertion site , Re-colonization , aqueous solution , article , catheter removal , catheterization , controlled study , disinfection , drug activity , epidural catheter , hair follicle , human , hypothesis , major clinical study , microbial colonization , microbiological examination , microflora , skin culture , skin surface , Catheters