Permanent atrial fibrillation portends poor outcomes in hospitalized patients with COVID-19: A retrospective observational study

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dc.contributor.authorÖzdemir İ.H.
dc.contributor.authorÖzlek B.
dc.contributor.authorÇetin N.
dc.date.accessioned2024-07-22T08:06:09Z
dc.date.available2024-07-22T08:06:09Z
dc.date.issued2021
dc.description.abstractBackground: Data specifically addressed to whether atrial fibrillation (AF) would contribute to increasing the risk for severe forms of novel coronavirus disease (COVID-19) or worse prognosis remain unclear. Hence, we sought to assess the association of permanent AF with in-hospital outcomes in patients with COVID-19. Methods: This was a single-centered, retrospective, observational study including consecutive hospitalized patients with COVID-19. The primary outcome for the study was defined as all cause in-hospital mortality. Clinical characteristics and outcomes of patients with AF were compared to patients without AF. Results: Three hundred and fifty hospitalized COVID-19 patients (median age of 55 years, 55.4% men) were enrolled. Of them 40 (11.4%) had AF. Patients with AF were older; were more likely to have co-morbidities, abnormal chest radiography findings and deteriorated laboratory parameters such as D-dimer, troponin, albumin, urea. In-hospital mortality was higher in patients with AF compared to patients without AF (32.5% vs. 13.5%, log-rank p = 0.002, RR 2.40). The number of patients who needed intensive care unit (55% vs. 31%, p = 0.002) and invasive mechanical ventilation (35% vs 15.2%, p = 0.002) were also higher in the AF group. In addition, length of in-hospital stay was longer in patients with AF (median 8 vs. 7 days, p = 0.008). After adjustment for age and co-morbidities, multivariable analyses revealed that AF (HR: 2.426, 95% CI: 1.089–5.405, p = 0.032) was independently associated with in-hospital death. Conclusions: AF was seen with together markers of severe COVID-19, and the presence of AF was an independent predictor of in-hospital mortality in patients with COVID-19. © 2021 Elsevier Inc.
dc.identifier.DOI-ID10.1016/j.jelectrocard.2021.01.016
dc.identifier.issn00220736
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13379
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.rightsAll Open Access; Green Open Access
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAtrial Fibrillation
dc.subjectCOVID-19
dc.subjectElectrocardiography
dc.subjectFemale
dc.subjectHeart Failure
dc.subjectHospital Mortality
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectRetrospective Studies
dc.subjectalbumin
dc.subjectC reactive protein
dc.subjectD dimer
dc.subjecttroponin I
dc.subjecturea
dc.subjectadult
dc.subjectArticle
dc.subjectcause of death
dc.subjectcomorbidity
dc.subjectcomputer assisted tomography
dc.subjectcontrolled study
dc.subjectcoronavirus disease 2019
dc.subjectdemography
dc.subjectdisease association
dc.subjectelectrocardiography
dc.subjectfemale
dc.subjecthospital mortality
dc.subjecthospitalization
dc.subjecthuman
dc.subjectintensive care unit
dc.subjectinvasive ventilation
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectobservational study
dc.subjectpermanent atrial fibrillation
dc.subjectretrospective study
dc.subjectthorax radiography
dc.subjectaged
dc.subjectatrial fibrillation
dc.subjectcomplication
dc.subjectheart failure
dc.subjecthospital mortality
dc.subjectmiddle aged
dc.subjectvery elderly
dc.subjectvirology
dc.titlePermanent atrial fibrillation portends poor outcomes in hospitalized patients with COVID-19: A retrospective observational study
dc.typeArticle

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