Correlation of the Volume Control Parameters with Health Related Quality of Life in Renal Transplant Patients
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Date
2015
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Abstract
Introduction Transplantation is the most effective treatment strategy for end-stage renal failure. We aimed to investigate the correlation of volume control parameters with health-related quality of life (HRQoL) in renal transplantation patients during the pre- and post-transplantation periods. Material and Methods Seventy-seven patients who underwent renal transplantation from deceased donors between January 2011 and January 2013 were included in the study. The biochemical markers, complete blood count, and creatinine levels were measured during pretransplantation and at post-transplantation month 6. The Turkish version of the Short Form 36 (SF-36) health survey questionnaire was used for the assessment of HRQoL. Blood pressure (BP) and echocardiographic measurements were used to evaluate the volume status. Results Significant improvements were achieved in all echocardiographic measurements, biochemical parameters except Ca++, and SF-36 questionnaire domain scores (DSs) except vitality in the post-transplantation period. Systolic BP (SBP), the left atrium index, vena cava inferior collapsibility index (VCCI), and diastolic BP were associated with vitality (P =.02,.03,.05, and.04, respectively); SBP was associated with social functioning (P <.01) and role emotional (P <.01); and left ventricular mass index was associated with mental health (P =.05) DSs during the pretransplantation period. In the post-transplantation period, VCCI, left ventricular mass index, and SBP were associated with general health (P =.02,.05, and.05, respectively); VCCI and SBP were also associated with mental health (P =.05 and.01, respectively); and left atrium index was associated with role emotional (P =.05) DSs. Conclusion Concomitant improvement in the volemic status may contribute to improvements in HRQoL after renal transplantation. © 2015 Elsevier Inc. All rights reserved.
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Adult , Cardiac Volume , Echocardiography , Female , Humans , Kidney Failure, Chronic , Kidney Transplantation , Male , Quality of Life , Surveys and Questionnaires , Treatment Outcome , biochemical marker , creatinine , adult , blood cell count , Conference Paper , correlational study , diastolic blood pressure , echocardiography , female , health survey , heart left atrium , heart left ventricle mass , human , inferior cava vein , kidney transplantation , major clinical study , male , mental health , postoperative period , priority journal , quality of life , questionnaire , Short Form 36 , social interaction , systolic blood pressure , heart volume , Kidney Failure, Chronic , kidney transplantation , physiology , psychology , treatment outcome