Prognostic Significance of Hemoglobin/Prognostic Nutritional Index and Hemoglobin/Red Blood Cell Distribution in Rectal Cancer

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dc.contributor.authorTuncel E.T.
dc.contributor.authorParvizi M.
dc.contributor.authorKut E.
dc.contributor.authorAydın M.
dc.contributor.authorKasap E.
dc.date.accessioned2024-07-22T08:03:09Z
dc.date.available2024-07-22T08:03:09Z
dc.date.issued2023
dc.description.abstractBackground: We aimed to investigate the effect of hemoglobin/prognostic nutritional index and hemoglobin/red blood cell distribution, which are indicators of inflammation and nutrition, on prognosis and survival in patients with rectal cancer. Methods: The retrospective study reviewed medical records of 138 patients with rectal cancer who were followed up between 2010 and 2021. The effects of hemoglobin/red blood cell distribution, hemoglobin/prognostic nutritional index, tumor stage, and lymph node status on survival and prognosis were evaluated using univariate and multivariate analyses. Overall survival and disease-free survival were calculated for both groups. Results: Survival and prognosis were found to be significantly better in nonanemic patients with the hemoglobin/prognostic nutritional index higher than the cut-off value than in anemic patients with a normal or lower hemoglobin/prognostic nutritional index. Similarly, survival and prognosis were found to be significantly better in nonanemic patients with a hemoglobin/red blood cell distribution higher than the cut-off value than in anemic patients with a normal or lower hemoglobin/red blood cell distribution. Conclusion: The results indicated that nutrition and inflammatory markers have independent prognostic significance in rectal cancer. These markers are simple, inexpensive, and useful biomarkers commonly used in clinical practice, and they were found to predict overall survival and disease-free survival independently. Copyright © Author(s)
dc.identifier.DOI-ID10.5152/TJG.2022.22203
dc.identifier.issn13004948
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12155
dc.language.isoEnglish
dc.publisherAVES
dc.rightsAll Open Access; Gold Open Access
dc.subjectErythrocytes
dc.subjectHemoglobins
dc.subjectHumans
dc.subjectNeoplasm Staging
dc.subjectNutrition Assessment
dc.subjectNutritional Status
dc.subjectPrognosis
dc.subjectRectal Neoplasms
dc.subjectRetrospective Studies
dc.subjectalbumin
dc.subjectbiological marker
dc.subjectCA 19-9 antigen
dc.subjectcarcinoembryonic antigen
dc.subjecthemoglobin
dc.subjectinflammatory marker
dc.subjecttumor marker
dc.subjectunclassified drug
dc.subjecthemoglobin
dc.subjectadult
dc.subjectaged
dc.subjectcancer prognosis
dc.subjectcancer specific survival
dc.subjectcancer staging
dc.subjectcancer survival
dc.subjectclinical assessment
dc.subjectclinical practice
dc.subjectclinical significance
dc.subjectConference Paper
dc.subjectdisease free survival
dc.subjectfemale
dc.subjecthuman
dc.subjectKolmogorov Smirnov test
dc.subjectleukocyte count
dc.subjectlymph vessel metastasis
dc.subjectlymphocyte
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmonocyte
dc.subjectmultivariate analysis
dc.subjectneoadjuvant chemotherapy
dc.subjectnutritional status
dc.subjectoverall survival
dc.subjectperineural invasion
dc.subjectplatelet count
dc.subjectprognostic significance
dc.subjectprognostic nutritional index
dc.subjectrectum anterior resection
dc.subjectrectum cancer
dc.subjectred blood cell distribution width
dc.subjectretrospective study
dc.subjectunivariate analysis
dc.subjecterythrocyte
dc.subjectnutritional assessment
dc.subjectnutritional status
dc.subjectprognosis
dc.subjectrectum tumor
dc.titlePrognostic Significance of Hemoglobin/Prognostic Nutritional Index and Hemoglobin/Red Blood Cell Distribution in Rectal Cancer
dc.typeConference paper

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