Diabetes mellitus adversely affects the outcomes of thrombolytic therapy in patients with acute myocardial infarction

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dc.contributor.authorTikiz H.
dc.contributor.authorTezcan U.
dc.contributor.authorIleri M.
dc.contributor.authorBalbay Y.
dc.contributor.authorAtak R.
dc.contributor.authorKütük E.
dc.date.accessioned2024-07-22T08:25:03Z
dc.date.available2024-07-22T08:25:03Z
dc.date.issued2003
dc.description.abstractThis study was performed to evaluate whether coexistent diabetes mellitus has any adverse effect on the outcomes of thrombolytic therapy in patients with acute myocardial infarction. Although the early reperfusion rates were similar between the two groups of patients who had acute myocardial infarction with and without diabetes mellitus (42% vs 45.4%, p > 0.05), the results of late angiographic examination showed a significantly lower rate of patency in infarct-related coronary artery (defined as TIMI 3 flow) in diabetics compared to nondiabetics (28.9% vs 41.3%, p < 0.001). The global left ventricular function was also poorer in diabetics (left ventricular wall motion score was 18.6 ± 7.3 in diabetics and 14.1 ± 4.6 in nondiabetics, p < 0.01).
dc.identifier.DOI-ID10.1177/000331970305400409
dc.identifier.issn00033197
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20255
dc.language.isoEnglish
dc.publisherWestminster Publications Inc.
dc.subjectacetylsalicylic acid
dc.subjectalteplase
dc.subjectbeta adrenergic receptor blocking agent
dc.subjectcalcium channel blocking agent
dc.subjectdipeptidyl carboxypeptidase inhibitor
dc.subjectheparin
dc.subjectinsulin
dc.subjectstreptokinase
dc.subjectthromboplastin
dc.subjectacute heart infarction
dc.subjectadult
dc.subjectaged
dc.subjectangiocardiography
dc.subjectarticle
dc.subjectblood vessel diameter
dc.subjectdiabetes mellitus
dc.subjectdisease association
dc.subjectdrug contraindication
dc.subjectfemale
dc.subjectfibrinolytic therapy
dc.subjectheart left ventricle function
dc.subjectheart muscle reperfusion
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectpartial thromboplastin time
dc.subjectpatient selection
dc.subjectscoring system
dc.subjecttreatment failure
dc.subjecttreatment outcome
dc.titleDiabetes mellitus adversely affects the outcomes of thrombolytic therapy in patients with acute myocardial infarction
dc.typeArticle

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