Prechondrogenic ATDC5 cell response to graphene/multi-walled carbon nanotube-containing porous polycaprolactone biocomposite scaffolds

dc.contributor.authorDeliormanlı A.M.
dc.contributor.authorAtmaca H.
dc.date.accessioned2024-07-22T08:08:13Z
dc.date.available2024-07-22T08:08:13Z
dc.date.issued2019
dc.description.abstractIn the study graphene and multi- walled carbon nanotube (MWCNT) - containing polycaprolactone (PCL) scaffolds were prepared by solvent casting-particulate leaching method for cartilage tissue engineering applications. Graphene nanopowders or MWCNTs were added to the system at different concentrations namely 1, 3, 5 and 10 wt%. Mechanical, thermal and electrical properties of the scaffolds were measured as a function of additive concentration. Response of prechondrogenic ATDC5 cells seeded on the composite constructs were tested using XTT method and live-dead cell viability assay. Alkaline phosphatase activity of the cells was also tested to investigate differentiation behaviour. Results showed that electrically conductive composite scaffolds prepared in the study have potential to be used in tissue engineering. © 2019, © 2019 Taylor & Francis Group, LLC.
dc.identifier.DOI-ID10.1080/00914037.2018.1539984
dc.identifier.issn00914037
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14302
dc.language.isoEnglish
dc.publisherTaylor and Francis Inc.
dc.subjectCartilage
dc.subjectCells
dc.subjectCytology
dc.subjectGraphene
dc.subjectNanotubes
dc.subjectPhosphatases
dc.subjectScaffolds
dc.subjectScaffolds (biology)
dc.subjectTissue
dc.subjectYarn
dc.subjectAdditive concentrations
dc.subjectAlkaline phosphatase activity
dc.subjectCartilage tissue engineering
dc.subjectElectrically conductive composites
dc.subjectMWCNT
dc.subjectPolycaprolactone scaffolds
dc.subjectSolvent casting particulate leaching methods
dc.subjectThermal and electrical properties
dc.subjectMultiwalled carbon nanotubes (MWCN)
dc.titlePrechondrogenic ATDC5 cell response to graphene/multi-walled carbon nanotube-containing porous polycaprolactone biocomposite scaffolds
dc.typeArticle

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