Effects of nitric oxide-vascular endothelial growth factor systems in chick embryo cerebral vasculogenesis and angiogenesis; [Civciv Embriyosunda Serebral Vaskülogenezis ve Anjiogenezis Üzerine Nitrik Oxid-Vasküler Endotelyal Growth Faktörün Etkileri]

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dc.contributor.authorTemiz C.
dc.contributor.authorArslan M.
dc.contributor.authorSayın M.
dc.contributor.authorVatansever S.
dc.contributor.authorGiray G.
dc.contributor.authorVar A.
dc.date.accessioned2024-07-22T08:19:22Z
dc.date.available2024-07-22T08:19:22Z
dc.date.issued2012
dc.description.abstractAim: Studies have depicted that nitric oxide and vascular endothelial growth factor systems have important biological effects in the development of vasculogenesis and angiogenesis. Material and Method: In this study; specific pathogen free white Leghorin type fertilised eggs were used. Result: Three main subgroups were designed regarding time points of 48; 72 and 80 hours of incubation. In 48 hours old embryos anjioblasts were seen; but no mature endothelial structure was present. In 72 hours old embryos endothelial maturation began. In the 80 hours there was a high level of endothelial maturation. In all 48 hours groups; tissue nitrite-nitrate concentrations were high but in the 72 hours group these values were higher than in the first group. In the 80 hours group; concentrations were lower and were statistically significant when compared to the 48 and 72 hours groups. Discussion: NO seems to be effective in early phases of vasculogenesis and angiogenesis; but its effect decreases with time. © 2012, Derman Medical Publishing. All rights reserved.
dc.identifier.DOI-ID10.4328/JCAM.778
dc.identifier.issn13090720
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17655
dc.language.isoEnglish
dc.publisherDerman Medical Publishing
dc.rightsAll Open Access; Bronze Open Access
dc.subjectnitrate
dc.subjectnitric oxide
dc.subjectnitrite
dc.subjectvasculotropin
dc.subjectangiogenesis
dc.subjectanimal experiment
dc.subjectanimal tissue
dc.subjectArticle
dc.subjectbrain blood vessel
dc.subjectchick embryo
dc.subjectcontrolled study
dc.subjectembryo
dc.subjectembryo development
dc.subjectfertilization
dc.subjectincubation time
dc.subjectnonhuman
dc.subjectvascular endothelium
dc.titleEffects of nitric oxide-vascular endothelial growth factor systems in chick embryo cerebral vasculogenesis and angiogenesis; [Civciv Embriyosunda Serebral Vaskülogenezis ve Anjiogenezis Üzerine Nitrik Oxid-Vasküler Endotelyal Growth Faktörün Etkileri]
dc.typeArticle

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