Corneal endothelial damage in phacoemulsification using an anterior chamber maintainer compared with using an ophthalmic viscosurgical device

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dc.contributor.authorMayali H.
dc.contributor.authorBaser E.F.
dc.contributor.authorKurt E.
dc.contributor.authorIlker S.S.
dc.date.accessioned2024-07-22T08:06:03Z
dc.date.available2024-07-22T08:06:03Z
dc.date.issued2021
dc.description.abstractPurpose: To compare the effects of phacoemulsification surgery (PE) using an anterior chamber maintainer (ACM) and conventional PE using an ophthalmic viscosurgical device (OVD) on corneal endothelial cells. Setting: Department of Ophthalmology, Celal Bayar University, Manisa, Turkey. Design: Prospective randomized controlled trial. Methods: Eyes in the OVD group (n = 50) underwent conventional PE, whereas eyes in the ACM group (n = 50) underwent PE using an ACM. Endothelial cell density (ECD), coefficient of variation (CV), hexagonality (HEX), and noncontact central corneal thickness (CCT) measurements were performed by specular microscopy before and at 1 month, 3 months, and 6 months after PE. Results: This study included 100 eyes of 97 patients undergoing PE. The mean age was 64.7 ± 10.6 years in the OVD group, 64.0 ± 12.6 years in the ACM group (P >.05). The groups did not differ significantly in preoperative ECD, CV, HEX, and CCT or total PE time (P >.05 for all). ECD was significantly lower in the ACM group compared with the OVD group at postoperative 1 month, 3 months, and 6 months (P =.002, P =.002, and P =.001, respectively). Similarly, ECD loss compared with preoperative value was greater in the ACM group at all postoperative timepoints (P =.003, P =.001, and P =.001, respectively). CV increased and HEX decreased in both groups postoperatively (P >.05 for both). CCT showed a transient increase of less than 10 m at postoperative 1 month in both groups (P =.296). Conclusions: PE with ACM was associated with greater corneal ECD loss compared with conventional PE. ACM should not be used during PE in patients with limited corneal endothelial reserve. © 2021 Elsevier Inc.. All rights reserved.
dc.identifier.DOI-ID10.1097/j.jcrs.0000000000000493
dc.identifier.issn08863350
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13364
dc.language.isoEnglish
dc.publisherLippincott Williams and Wilkins
dc.subjectAnterior Chamber
dc.subjectCell Count
dc.subjectEndothelial Cells
dc.subjectEndothelium, Corneal
dc.subjectHumans
dc.subjectLens Implantation, Intraocular
dc.subjectMiddle Aged
dc.subjectPhacoemulsification
dc.subjectProspective Studies
dc.subjectbupivacaine
dc.subjectcyclopentolate
dc.subjectdexamethasone
dc.subjectepinephrine
dc.subjectgentamicin
dc.subjectlidocaine
dc.subjectmoxifloxacin
dc.subjectprednisolone sodium phosphate
dc.subjecttropicamide
dc.subjectadult
dc.subjectArticle
dc.subjectcell density
dc.subjectcentral corneal thickness
dc.subjectcontrolled study
dc.subjectcornea endothelium
dc.subjectcorneal endothelial cell loss
dc.subjectendothelium cell
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmiddle aged
dc.subjectphacoemulsification
dc.subjectpostoperative complication
dc.subjectpreoperative evaluation
dc.subjectprospective study
dc.subjectrandomized controlled trial
dc.subjectsenile cataract
dc.subjectspecular microscopy
dc.subjectanterior eye chamber
dc.subjectcell count
dc.subjectlens implantation
dc.titleCorneal endothelial damage in phacoemulsification using an anterior chamber maintainer compared with using an ophthalmic viscosurgical device
dc.typeArticle

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