Prevalence of depression and anxiety in patients with cystic fibrosis and parent caregivers: Results of the International Depression Epidemiological Study across nine countries

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dc.contributor.authorQuittner A.L.
dc.contributor.authorGoldbeck L.
dc.contributor.authorAbbott J.
dc.contributor.authorDuff A.
dc.contributor.authorLambrecht P.
dc.contributor.authorSolé A.
dc.contributor.authorTibosch M.M.
dc.contributor.authorBrucefors A.B.
dc.contributor.authorYüksel H.
dc.contributor.authorCatastini P.
dc.contributor.authorBlackwell L.
dc.contributor.authorBarker D.
dc.date.accessioned2024-07-22T08:14:29Z
dc.date.available2024-07-22T08:14:29Z
dc.date.issued2014
dc.description.abstractBackground: Individuals with chronic diseases and parent caregivers are at increased risk for symptoms of depression and anxiety. Prevalence of psychological symptoms was evaluated in adolescents and adults with cystic fibrosis (CF) and parent caregivers across nine countries. Methods: Patients with CF, ages 12 years and older, and caregivers of children with CF, birth to18 years of age, completed measures of depression and anxiety across 154 CF centres in Europe and the USA. Psychological symptoms were compared across countries using χ2. Logistic regression examined extent of comorbid symptoms, predictors of depression and anxiety, and concordance between parent and adolescent symptomatology. Results: Psychological symptoms were reported by 6088 patients with CF and 4102 parents. Elevated symptoms of depression were found in 10% of adolescents, 19% of adults, 37% of mothers and 31% of fathers. Elevations in anxiety were found in 22% of adolescents, 32% of adults, 48% of mothers and 36% of fathers. Overall, elevations were 2-3 times those of community samples. Participants reporting elevated anxiety were more likely to report depression (ORs: adolescents=14.97, adults=13.64, mothers=15.52, fathers=9.20). Significant differences in reports of depression and anxiety were found by patient age and parent respondent. Concordance between 1122 parent-teen dyads indicated that adolescents whose parents reported depression were more likely to be elevated on depression (OR=2.32). Similarly, adolescents whose parents reported anxiety were more likely to score in the elevated range on the anxiety measure (OR=2.22). Conclusions: Symptoms of depression and anxiety were elevated in both patients with CF and parents across several European countries and the USA. Annual screening of psychological symptoms is recommended for both patients and parents. © 2014, BMJ Publishing Group. All rights reserved.
dc.identifier.DOI-ID10.1136/thoraxjnl-2014-205983
dc.identifier.issn00406376
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16573
dc.language.isoEnglish
dc.publisherBMJ Publishing Group
dc.rightsAll Open Access; Bronze Open Access
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAnxiety
dc.subjectCaregivers
dc.subjectChild
dc.subjectComorbidity
dc.subjectCystic Fibrosis
dc.subjectDepression
dc.subjectEurope
dc.subjectFamily Health
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectParents
dc.subjectPrevalence
dc.subjectPsychiatric Status Rating Scales
dc.subjectRisk Factors
dc.subjectTurkey
dc.subjectUnited States
dc.subjectYoung Adult
dc.subjectadolescent
dc.subjectadult
dc.subjectanxiety
dc.subjectArticle
dc.subjectBelgium
dc.subjectcaregiver
dc.subjectcaregiver burden
dc.subjectcomorbidity
dc.subjectcystic fibrosis
dc.subjectdepression
dc.subjectdisease association
dc.subjectdisease severity
dc.subjectepidemiological monitoring
dc.subjectfemale
dc.subjectGermany
dc.subjecthigh risk population
dc.subjecthuman
dc.subjectItaly
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectNetherlands
dc.subjectpredictor variable
dc.subjectprevalence
dc.subjectpsychologic assessment
dc.subjectpsychological well being
dc.subjectrisk factor
dc.subjectSpain
dc.subjectSweden
dc.subjectsymptomatology
dc.subjectTurkey (republic)
dc.subjectUnited Kingdom
dc.subjectUnited States
dc.subjectanxiety
dc.subjectcaregiver
dc.subjectchild
dc.subjectclinical trial
dc.subjectcystic fibrosis
dc.subjectdepression
dc.subjectepidemiology
dc.subjectetiology
dc.subjectEurope
dc.subjectfamily health
dc.subjectmiddle aged
dc.subjectmulticenter study
dc.subjectparent
dc.subjectpsychological rating scale
dc.subjectpsychology
dc.subjectstatistics and numerical data
dc.subjectTurkey
dc.subjectyoung adult
dc.titlePrevalence of depression and anxiety in patients with cystic fibrosis and parent caregivers: Results of the International Depression Epidemiological Study across nine countries
dc.typeArticle

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