Seawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline

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dc.contributor.authorCingi C.
dc.contributor.authorHalis Unlu H.
dc.contributor.authorSongu M.
dc.contributor.authorYalcin S.
dc.contributor.authorTopcu I.
dc.contributor.authorCakli H.
dc.contributor.authorBal C.
dc.date.accessioned2024-07-22T08:21:16Z
dc.date.available2024-07-22T08:21:16Z
dc.date.issued2010
dc.description.abstractObjective: We performed a prospective study to investigate the the efficacy of seawater gel in reducing symptoms in patients with mild allergic rhinitis. We also aimed to investigate the impact of nasal irrigation on mucociliary clearance with seawater gel compared with saline in this patient group. Methods: The study was performed in 100 consecutive adult individuals with a history of allergic rhinitis that was not controlled by anti-allergic drugs. Patients were assigned to receive seawater gel nasal spray for 10 days. The efficacy of treatment was assessed by means of total nasal symptom score and clinical findings. Results: A statistically significant difference was found between scores of ‘nasal discharge, nasal obstruction, sneezing, nasal itching—before and after treatment (p < 0.001). Clinical findings evaluation revealed a statistically significant decrease in lower turbinate colour rating and turbinate congestion at the end of treatment (p< 0.001). Saccharin transit time decreased from baseline in the seawater trials by 12% compared with a 4% decrease for saline. The difference between the percent changes was statistically significant (t = 2.177; p < 0.05). Conclusions: The present study provides evidence that a four times daily regimen of seawater gel can be an adjunctive therapy in the patient with allergic rhinitis. © 2010, SAGE Publications. All rights reserved.
dc.identifier.DOI-ID10.1177/1753465809358190
dc.identifier.issn17534658
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18541
dc.language.isoEnglish
dc.subjectAdministration, Intranasal
dc.subjectAdolescent
dc.subjectAdult
dc.subjectFemale
dc.subjectHumans
dc.subjectIrrigation
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMucociliary Clearance
dc.subjectNasal Cavity
dc.subjectNasal Obstruction
dc.subjectProspective Studies
dc.subjectRhinitis, Allergic, Seasonal
dc.subjectSaccharin
dc.subjectSeawater
dc.subjectSneezing
dc.subjectSodium Chloride
dc.subjectTreatment Outcome
dc.subjectYoung Adult
dc.subjectsea water
dc.subjectsodium chloride
dc.subjectadult
dc.subjectallergic rhinitis
dc.subjectarticle
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectfemale
dc.subjecthuman
dc.subjectlavage
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmucociliary clearance
dc.subjectnose congestion
dc.subjectnose obstruction
dc.subjectpriority journal
dc.subjectprospective study
dc.subjectpruritus
dc.subjectsneezing
dc.subjecttherapy effect
dc.titleSeawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline
dc.typeArticle

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