The effects of magnesium sulphate on postoperative analgesia; [Magnezyum sulfatin postoperatif analjeziye etkileri]

Simple item page
dc.contributor.authorTekin I.
dc.contributor.authorErbuyun K.
dc.contributor.authorOruc S.
dc.contributor.authorToprak V.
dc.contributor.authorAlincak H.
dc.date.accessioned2024-07-22T08:25:42Z
dc.date.available2024-07-22T08:25:42Z
dc.date.issued2000
dc.description.abstractIt has been suggested that magnesium with its calcium channel blocking and NMDA antagonist properties could play a role in prevention and treatment of pain. We assessed the effect of perioperative IV magnesium sulfate on the early period of postoperative analgesia. ASA I or II class, at least graduated from secondary school, 30 patients, undergoing elective abdominal hysterectomy with TIVA (total intravenous anaesthesia), received standard premedication. We added saline (group I, n:15) or 15 % MgS04 (group II, n:15), 15 mL IV bolus after induction agents and 3 mL/h IV infusion at the end of the postoperative 6th hour. PCA (patient controlled analgesia) with fentanyl was used for postoperative analgeesia. Peroperative hemodynamic data, total propofol, fentanyl and vecuronium doses are noted. VAS (visuel analog scale) was used to assess postoperative pain and sedation scale for sedation assessment in postoperative 30. minutes and 2-4-6. hours. Determination of serum magnesium-concentration were obtained before the start Of the intravenous study drug treatment and after the end of the infusion. There were no differences in demographic data, ASA classification, duration of surgery, intraoperatif total propofol, fentanyl and vecuronium doses between two groups. Postoperative demand, delivery and total fentanyl levels were higher in group I (p<0.05). VAS and SS were similar in two groups. At the end of the infusion serum magnesium concentrations were higher than preoperative values in group II (p<0.05). In this study we found that magnesium-reduces postoperative analgesic requirements without adverse effects. In conclusion, magnesium is a good adjuan analgesic agent and will gain a popularity in the early future with new studies.
dc.identifier.issn10165150
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20557
dc.language.isoTurkish
dc.subjectfentanyl derivative
dc.subjectmagnesium sulfate
dc.subjectn methyl dextro aspartic acid receptor blocking agent
dc.subjectpropofol
dc.subjectsodium chloride
dc.subjectvecuronium
dc.subjectabdominal hysterectomy
dc.subjectadjuvant therapy
dc.subjectarticle
dc.subjectclinical article
dc.subjectdemography
dc.subjectdrug blood level
dc.subjectdrug disposition
dc.subjecthemodynamic monitoring
dc.subjecthuman
dc.subjectintraoperative period
dc.subjectintravenous anesthesia
dc.subjectmagnesium blood level
dc.subjectpain assessment
dc.subjectpostoperative analgesia
dc.subjectpremedication
dc.subjectpreoperative care
dc.subjectsedation
dc.titleThe effects of magnesium sulphate on postoperative analgesia; [Magnezyum sulfatin postoperatif analjeziye etkileri]
dc.typeArticle

Files

Collections

Scopus Koleksiyonu