Interleukin-6 levels in hyperemesis gravidarum
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Date
2003
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Abstract
Introduction: Hyperemesis gravidarum (HG) is associated with higher levels of serum β-hCG levels and hyperthyroidism. Interleukin-6 (IL-6), a pro-inflammatory cytokine, is reported to enhance secretion of β-hCG from trophoblastic cell line. Methods: We measured serum levels of IL-6, thyroid hormones and β-hCG of hyperemetic patients and gestational age-matched controls to search for a difference between the two groups. Results: There was a significant difference in β-hCG (p=0.028), though IL-6 levels were higher in the hyperemetic group, it did not reach a significant level. Interleukin-6 positively correlated with β-hCG (r=0.38 and p=0.13).
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Adult , Chorionic Gonadotropin , Female , Humans , Hyperemesis Gravidarum , Interleukin-6 , Pregnancy , Pregnancy Trimester, First , Statistics, Nonparametric , Thyrotropin , Thyroxine , Triiodothyronine , chorionic gonadotropin beta subunit , interleukin 6 , thyroid hormone , adult , article , clinical article , controlled study , correlation analysis , disease association , female , gestational age , hormone release , human , hyperemesis gravidarum , hyperthyroidism , trophoblast