The associations between endogenous oxytocin levels and emotion recognition in bipolar disorder

Simple item page
dc.contributor.authorTas C.
dc.contributor.authorBrown E.C.
dc.contributor.authorOnur E.
dc.contributor.authorAydemir O.
dc.contributor.authorBrune M.
dc.date.accessioned2024-07-22T08:14:38Z
dc.date.available2024-07-22T08:14:38Z
dc.date.issued2015
dc.description.abstractObjective: Recent studies in patients with Bipolar Disorder (BD) have revealed problems in emotion recognition, specifically for negative emotions, which have been subsequently related to amygdala activity. Previously, the prosocial neuropeptide oxytocin has been shown to be one hormone that alters emotion perception capacities and modulates amygdala response. Accordingly, the aim of this study was to see if plasma oxytocin levels have specific effects on predicting emotion recognition patterns in BD. Methods: Twenty-eight remitted BD patients were recruited for this study and the Vienna Emotion Recognition Task was given. In addition, blood samples were collected for plasma oxytocin analysis. Results: Strong associations were found between fearful emotions and basal oxytocin levels, which were supported by a stepwise regression analysis. Patients with higher levels of basal oxytocin also exhibited greater recognition of fearful emotions. Conclusions: The relationship between recognition of fearful faces and individual endogenous oxytocin levels may contribute to explaining individual differences in social functioning and amygdala dysfunction in BD. © 2015, Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali. All rights reserved.
dc.identifier.DOI-ID10.5455/bcp.20140514043545
dc.identifier.issn10177833
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16630
dc.language.isoEnglish
dc.publisherCukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali
dc.subjectlamotrigine
dc.subjectlithium
dc.subjectmood stabilizer
dc.subjectoxytocin
dc.subjectquetiapine
dc.subjectvalproic acid
dc.subjectadult
dc.subjectamygdaloid nucleus
dc.subjectArticle
dc.subjectbipolar disorder
dc.subjectblood sampling
dc.subjectclinical article
dc.subjectdata analysis
dc.subjectdisease duration
dc.subjectdisgust
dc.subjectemotion assessment
dc.subjectfear
dc.subjectfemale
dc.subjecthappiness
dc.subjecthuman
dc.subjectmale
dc.subjectmental task
dc.subjectmultivariate analysis of covariance
dc.subjectoxytocin blood level
dc.subjectsadness
dc.subjectschizoaffective psychosis
dc.subjectStructured Clinical Interview for DSM Disorders
dc.subjectvienna emotion recognition task
dc.titleThe associations between endogenous oxytocin levels and emotion recognition in bipolar disorder
dc.typeArticle

Files

Collections

Scopus Koleksiyonu