Direct-write assembly of silicate and borate bioactive glass scaffolds for bone repair

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dc.contributor.authorDeliormanli A.M.
dc.contributor.authorRahaman M.N.
dc.date.accessioned2024-07-22T08:19:23Z
dc.date.available2024-07-22T08:19:23Z
dc.date.issued2012
dc.description.abstractSilicate (13-93) and borate (13-93B3) bioactive glass scaffolds were created by robotic deposition (robocasting) of organic solvent-based suspensions and evaluated in vitro for potential application in bone repair. Suspensions (inks) were developed, characterized, and deposited layer-by-layer to form three-dimensional scaffolds with a grid-like microstructure (porosity ≈50%; pore width 420 ± 30 μm). The mechanical response of the scaffolds was tested in compression, and the conversion of the glass to hydroxyapatite (HA)-like material in a simulated body fluid (SBF) was evaluated. As fabricated, the 13-93 scaffolds had a compressive strength 142 ± 20. MPa, comparable to the strength of human cortical bone, while the strength of the 13-93B3 scaffolds (65 ± 11. MPa), was far higher than that for trabecular bone. When immersed in SBF, the borate 13-93B3 scaffolds converted faster than the silicate 13-93 scaffolds to an HA-like material, but they also showed a sharper decrease in strength with immersion time. Based on their high compressive strength and bioactivity, the scaffolds fabricated in this work by robocasting could have potential application in the repair of load-bearing bone. © 2012 Elsevier Ltd.
dc.identifier.DOI-ID10.1016/j.jeurceramsoc.2012.05.005
dc.identifier.issn09552219
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17661
dc.language.isoEnglish
dc.subjectBioactive glass
dc.subjectBone
dc.subjectCompressive strength
dc.subjectHydroxyapatite
dc.subjectLayered manufacturing
dc.subjectOrganic solvents
dc.subjectScaffolds
dc.subjectSilicates
dc.subjectBone repair
dc.subjectDirect-write assembly
dc.subjectGrid-like
dc.subjectHuman cortical bone
dc.subjectImmersion time
dc.subjectIn-vitro
dc.subjectLayer-by-layers
dc.subjectLoad-bearing
dc.subjectMechanical response
dc.subjectPore width
dc.subjectPotential applications
dc.subjectRobocasting
dc.subjectRobotic deposition
dc.subjectSimulated body fluids
dc.subjectSolvent based
dc.subjectThree-dimensional scaffolds
dc.subjectTrabecular bones
dc.subjectScaffolds (biology)
dc.titleDirect-write assembly of silicate and borate bioactive glass scaffolds for bone repair
dc.typeArticle

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