Predicting hospitalization in children with acute asthma

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dc.contributor.authorBuyuktiryaki A.B.
dc.contributor.authorCivelek E.
dc.contributor.authorCan D.
dc.contributor.authorOrhan F.
dc.contributor.authorAydogan M.
dc.contributor.authorReisli I.
dc.contributor.authorKeskin O.
dc.contributor.authorAkcay A.
dc.contributor.authorYazicioglu M.
dc.contributor.authorCokugras H.
dc.contributor.authorYuksel H.
dc.contributor.authorZeyrek D.
dc.contributor.authorKocak A.K.
dc.contributor.authorSekerel B.E.
dc.date.accessioned2024-07-22T08:18:29Z
dc.date.available2024-07-22T08:18:29Z
dc.date.issued2013
dc.description.abstractBackground: Acute asthma is one of the most common medical emergencies in children. Appropriate assessment/treatment and early identification of factors that predict hospitalization are critical for the effective utilization of emergency services. Objective: To identify risk factors that predict hospitalization and to compare the concordance of the Modified Pulmonary Index Score (MPIS) with the Global Initiative for Asthma (GINA) guideline criteria in terms of attack severity. Methods: The study population was composed of children aged 5-18 years who presented to the Emergency Departments (ED) of the tertiary reference centers of the country within a period of 3 months. Patients were evaluated at the initial presentation and the 1st and 4th hours. Results: Of the 304 patients (median age: 8.0 years [interquartile range: 6.5-9.7]), 51.3% and 19.4% required oral corticosteroids (OCS) and hospitalization, respectively. Attack severity and MPIS were found as predicting factors for hospitalization, but none of the demographic characteristics collected predicted OCS use or hospitalization. Hospitalization status at the 1st hour with moderate/severe attack severity showed a sensitivity of 44.1%, specificity of 82.9%, positive predictive value of 38.2%, and negative predictive value of 86.0%; for MPIS ≥ 5, these values were 42.4%, 85.3%, 41.0%, and 86.0%, respectively. Concordance in prediction of hospitalization between the MPIS and the GINA guideline was found to be moderate at the 1 st hour (κ = 0.577). Conclusion: Attack severity is a predictive factor for hospitalization in children with acute asthma. Determining attack severity with MPIS and a cut-off value ≥ 5 at the 1st hour may help physicians in EDs. Having fewer variables and the ability to calculate a numeric value with MPIS makes it an easy and useful tool in clinical practice. © 2013 Published by Elsevier Inc.
dc.identifier.DOI-ID10.1016/j.jemermed.2012.10.015
dc.identifier.issn07364679
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17319
dc.language.isoEnglish
dc.subjectAdolescent
dc.subjectAsthma
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectEmergency Service, Hospital
dc.subjectFemale
dc.subjectGlucocorticoids
dc.subjectHospitalization
dc.subjectHumans
dc.subjectMale
dc.subjectPractice Guidelines as Topic
dc.subjectPredictive Value of Tests
dc.subjectRisk Factors
dc.subjectROC Curve
dc.subjectSensitivity and Specificity
dc.subjectSeverity of Illness Index
dc.subjectTurkey
dc.subjectcorticosteroid
dc.subjectacute disease
dc.subjectarticle
dc.subjectasthma
dc.subjectchild
dc.subjectclinical feature
dc.subjectdisease severity
dc.subjectemergency care
dc.subjectfemale
dc.subjectGlobal Initiative for Asthma
dc.subjecthospitalization
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectModified Pulmonary Index Score
dc.subjectpractice guideline
dc.subjectpredictive value
dc.subjectpreschool child
dc.subjectpriority journal
dc.subjectschool child
dc.subjectscoring system
dc.subjectsensitivity and specificity
dc.titlePredicting hospitalization in children with acute asthma
dc.typeArticle

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