Advanced oxidation protein products, ferrous oxidation in xylenol orange, and malondialdehyde levels in thyroid cancer

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dc.contributor.authorKosova F.
dc.contributor.authorÇetin B.
dc.contributor.authorAkinci M.
dc.contributor.authorAslan S.
dc.contributor.authorAri Z.
dc.contributor.authorSepici A.
dc.contributor.authorAltan N.
dc.contributor.authorÇetin A.
dc.date.accessioned2024-07-22T08:22:49Z
dc.date.available2024-07-22T08:22:49Z
dc.date.issued2007
dc.description.abstractAims and Background: The oxidation of protein plays an essential role in the pathogenesis of an important number of degenerative and cancer diseases, which is now widely recognized. The aim is to examine advanced oxidation protein products (AOPPs), lipid peroxidation products malondialdehyde (MDA), and ferrous oxidation in xylenol orange (FOX) in blood samples of papillary thyroid cancer patients compared with healthy controls to determine the oxidation status and the change after thyroidectomy. Methods: Thirty-five female thyroid cancer patients who underwent total thyroidectomy and 39 female control subjects were included into this study. Prethyroidectomy and postthyroidectomy, AOPP, FOX, and MDA levels were studied. Results: Prethyroidectomy AOPP, FOX, and MDA levels were significantly higher compared to control (P < .05). In postthyroidectomy AOPP, FOX, and MDA levels were significantly decreased compared with prethyroidectomy levels (P < .05). However, postthyroidectomy levels on the 20th day were still significantly higher, compared to control subjects (P < .05). Conclusion: In conclusion, all of AOPP, FOX, and MDA levels that are markers of protein oxidation and lipid hyperoxidation may induce thyroid cancer development and begin to decrease after thyroidectomy. © 2007 Society of Surgical Oncology.
dc.identifier.DOI-ID10.1245/s10434-007-9425-5
dc.identifier.issn15344681
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19257
dc.language.isoEnglish
dc.subjectAdult
dc.subjectBlood Proteins
dc.subjectFemale
dc.subjectFerrous Compounds
dc.subjectHumans
dc.subjectLipid Peroxidation
dc.subjectMale
dc.subjectMalondialdehyde
dc.subjectOxidation-Reduction
dc.subjectRadioimmunoassay
dc.subjectStatistics, Nonparametric
dc.subjectThyroid Neoplasms
dc.subjectThyroidectomy
dc.subjectTumor Markers, Biological
dc.subjectXylenes
dc.subjectadvanced oxidation protein product
dc.subjectceruloplasmin
dc.subjectmalonaldehyde
dc.subjecttumor marker
dc.subjectunclassified drug
dc.subjectadult
dc.subjectarticle
dc.subjectblood sampling
dc.subjectcancer research
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectdisease course
dc.subjectfemale
dc.subjecthuman
dc.subjectlipid peroxidation
dc.subjectoxidation
dc.subjectpostoperative period
dc.subjectpreoperative period
dc.subjectthyroid cancer
dc.subjectthyroidectomy
dc.titleAdvanced oxidation protein products, ferrous oxidation in xylenol orange, and malondialdehyde levels in thyroid cancer
dc.typeArticle

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