Asthma-chronic obstructive pulmonary disease overlap: Results from a national-multicenter study; [Astım KOAH overlap: Ulusal çok merkezli bir çalışma sonuçları]

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dc.contributor.authorÇelik G.E.
dc.contributor.authorAydin Ö.
dc.contributor.authorŞen E.
dc.contributor.authorDemir T.
dc.contributor.authorGemicioğlu B.
dc.contributor.authorKiyan E.
dc.contributor.authorMungan D.
dc.contributor.authorKivilcim Oğuzülgen İ.
dc.contributor.authorPolatli M.
dc.contributor.authorGöksel Ö.
dc.contributor.authorSayiner A.
dc.contributor.authorYildirim N.
dc.contributor.authorYildiz F.
dc.contributor.authorYorgancioğlu A.
dc.contributor.authorElhan A.H.
dc.contributor.authorYildiz Ö.
dc.contributor.authorBaşyiğit İ.
dc.contributor.authorBörekçi Ş.
dc.contributor.authorHavlucu Y.
dc.contributor.authorOkumuş G.
dc.contributor.authorTürk M.
dc.contributor.authorSaryal S.
dc.date.accessioned2024-07-22T08:01:52Z
dc.date.available2024-07-22T08:01:52Z
dc.date.issued2024
dc.description.abstractIntroduction: Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) have a greater disease burden than those with COPD or asthma alone. In this study, it was aimed to determine the prevalence, risk factors, and clinical features of ACO because there are limited national data in Türkiye. Materials and Methods: The study was conducted in a cross-sectional design in nine tertiary-care hospitals. The patients followed with a diagnosis of asthma or COPD for at least one year were enrolled in the study. The frequency of ACO and the characteristics of the patients were evaluated in the asthma and COPD groups. Results: The study included 408 subjects (F/M= 205/203, mean age= 56.24 ± 11.85 years). The overall prevalence of ACO in both groups was 20.8% (n= 85). The frequency was higher in the COPD group than in the asthma group (n= 55; 33.3% vs. n= 22; 9.8%), respectively (p= 0.001). Patients with ACO had similarities to patients with COPD in terms of advanced age, sex, smoking, exposure to biomass during childhood, being born in rural areas, and radio-logic features. Characteristics such as a history of childhood asthma and allergic rhinitis, presence of chronic sinusitis, NSAID hypersensitivity, atopy, and high eosinophil counts were similar to those of patients with asthma (p< 0.001). The annual decline in FEV1 was more prominent in the ACO group (mean=-250 mL) than in the asthma (mean change=-60 mL) and COPD (mean change=-230 mL) groups (p= 0.003). Conclusion: This study showed that ACO was common among patients with asthma and COPD in tertiary care clinics in our country. ACO should be considered in patients with asthma and COPD who exhibit the abovementioned symptoms. © 2024 by Tuberculosis and Thorax.
dc.identifier.DOI-ID10.5578/tt.202401886
dc.identifier.issn04941373
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11626
dc.language.isoEnglish
dc.publisherAnkara University
dc.rightsAll Open Access; Gold Open Access
dc.subjectAdult
dc.subjectAged
dc.subjectAsthma
dc.subjectAsthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome
dc.subjectCross-Sectional Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPrevalence
dc.subjectPulmonary Disease, Chronic Obstructive
dc.subjectRisk Factors
dc.subjectTurkey
dc.subjectcorticosteroid
dc.subjecthemoglobin
dc.subjectnonsteroid antiinflammatory agent
dc.subjectadult
dc.subjectaged
dc.subjectallergic rhinitis
dc.subjectanxiety
dc.subjectArticle
dc.subjectasthma
dc.subjectbiomass
dc.subjectbody burden
dc.subjectbronchiectasis
dc.subjectcancer cell
dc.subjectchronic obstructive lung disease
dc.subjectchronic sinusitis
dc.subjectcross-sectional study
dc.subjectdemographics
dc.subjectdepression
dc.subjectemergency ward
dc.subjectemphysema
dc.subjecteosinophil
dc.subjectfemale
dc.subjecthematocrit
dc.subjecthospitalization
dc.subjecthuman
dc.subjecthypersensitivity
dc.subjecthypertension
dc.subjectinterstitial lung disease
dc.subjectlung function test
dc.subjectmale
dc.subjectprevalence
dc.subjectrisk factor
dc.subjectundifferentiated connective tissue disease
dc.subjectasthma
dc.subjectasthma-chronic obstructive pulmonary disease overlap syndrome
dc.subjectchronic obstructive lung disease
dc.subjectclinical trial
dc.subjectcomplication
dc.subjectmiddle aged
dc.subjectmulticenter study
dc.subjectturkey (bird)
dc.titleAsthma-chronic obstructive pulmonary disease overlap: Results from a national-multicenter study; [Astım KOAH overlap: Ulusal çok merkezli bir çalışma sonuçları]
dc.typeArticle

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