Synthesis and some reactions of 4-(ethoxycarbonyl)-1,5-diphenyl- 1H-pyrazole-3-carboxylic acid

Simple item page
dc.contributor.authorŞener A.
dc.contributor.authorTozlu I.
dc.contributor.authorGenç H.
dc.contributor.authorBildirici I.
dc.contributor.authorArisoy K.
dc.date.accessioned2024-07-22T08:22:58Z
dc.date.available2024-07-22T08:22:58Z
dc.date.issued2007
dc.description.abstract(Chemical Equation Presented) 1,5-Diphenyl-1H-pyrazole-3,4-dicarboxylic acid-4-ethyl ester 2, obtained from the 4-ethoxycarbonyl-5-phenyl-2,3-furandione 1 and N-benzylidene-N1-phenyl hydrazine, was converted via reactions of its acid chloride 3 with various alcohols or N-nucleophiles into the corresponding ester 5 or amide derivatives 6, respectively. In addition, 2 was decarboxylated to give ethyl 1,5-diphenylpyrazole-4-carboxylate 4. Nitrile 7 derivative of 2 was also obtained by dehydration of 6a in a mixture of SOCl 2 and DMF. While cyclocondensation reaction of 2 with hydrazine hydrate leads to the formation of pyrazolo[3,4-d]pyridazine-4,7-dione 8, the reaction of 3 with anhydrous hydrazine provided a new bis pyrazole derivative 9.
dc.identifier.DOI-ID10.1002/jhet.5570440516
dc.identifier.issn0022152X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19317
dc.language.isoEnglish
dc.publisherHeteroCorporation
dc.subject1,5 diphenyl 1h pyrazole 3,4 dicarboxylic acid 4 ethyl ester
dc.subject4 (ethoxycarbonyl) 1,5 diphenyl 1h pyrazole 3 carboxylic acid
dc.subject4 ethoxycarbonyl 5 phenyl 2,3 furandione
dc.subjectalcohol derivative
dc.subjectamide
dc.subjectcarboxylic acid derivative
dc.subjectester derivative
dc.subjectethyl 1,5 diphenylpyrazole 4 carboxylate
dc.subjecthydrazine
dc.subjectn benzylidene n' phenylhydrazine
dc.subjectn,n dimethylformamide
dc.subjectnitrile
dc.subjectphenylhydrazine derivative
dc.subjectpyrazole derivative
dc.subjectpyrazolo[3,4 d]pyridazine 4,7 dione
dc.subjectpyrrole derivative
dc.subjectunclassified drug
dc.subjectarticle
dc.subjectchemical reaction
dc.subjectchemical structure
dc.subjectpolymerization
dc.subjectreaction analysis
dc.subjectsynthesis
dc.titleSynthesis and some reactions of 4-(ethoxycarbonyl)-1,5-diphenyl- 1H-pyrazole-3-carboxylic acid
dc.typeArticle

Files

Collections

Scopus Koleksiyonu