New treatment alternatives in the management of non-i̇nfectious i̇ntraocular i̇nflammations: Biologic agents; [Enfeksiyöz olmayan i̇ntraoküler i̇nflamasyonlarin kontrolünde yeni seçenekler: Biyolojik ajanlar]

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dc.contributor.authorEmre S.
dc.contributor.authorTutkun I.T.
dc.date.accessioned2024-07-22T08:20:13Z
dc.date.available2024-07-22T08:20:13Z
dc.date.issued2011
dc.description.abstractConventional immunosuppressive agents have been traditionally used for the treatment of noninfectious uveitis. Recent developments in genetic engineering have made it possible to synthesize proteins that target specific molecules playing role in the inflammatory response. These agents are generally in protein structure and are named biologic agents. While there is limited experience with biologics in the field of ophthalmology, they are commonly used in other disciplines such as rheumatology and dermatology. Although considerable data have accumulated in the uveitis literature regarding the use of biologic agents, including mainly interferon, infliximab, and adalimumab, their use for this indication is still off-label. Moreover, there are certain precautions that have to be taken into account, as well as important safety issues associated with their use. The purpose of this paper is to present an updated comprehensive review of biologic agents that may be used for the treatment of refractory uveitis.
dc.identifier.DOI-ID10.4274/tjo.41.21931
dc.identifier.issn13000659
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18058
dc.language.isoEnglish
dc.rightsAll Open Access; Gold Open Access
dc.subjectadalimumab
dc.subjectinfliximab
dc.subjectinterferon
dc.subjectalternative medicine
dc.subjectdrug indication
dc.subjectdrug safety
dc.subjectdrug targeting
dc.subjectdrug use
dc.subjecteye inflammation
dc.subjectgenetic engineering
dc.subjecthuman
dc.subjectprotein structure
dc.subjectprotein synthesis
dc.subjectreview
dc.subjectuveitis
dc.titleNew treatment alternatives in the management of non-i̇nfectious i̇ntraocular i̇nflammations: Biologic agents; [Enfeksiyöz olmayan i̇ntraoküler i̇nflamasyonlarin kontrolünde yeni seçenekler: Biyolojik ajanlar]
dc.typeReview

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