Stage is a prognostic factor for surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status has been implemented
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Date
2017
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Abstract
Objectives: To determine the locoregional control and survival rates (in terms of risk factors) of patients who underwent surgical resection of early-stage lip cancer and for whom a 'wait and see' policy in terms of neck status had been implemented. Methods: The sociodemographic data, tumour stage, tumour characteristics and histopathological features of 41 patients with early-stage lip cancer were evaluated. Factors predictive of survival and locoregional recurrence were analysed. The five-year overall survival and disease-free survival rates were determined, and the prognostic risk factors were compared. Results: The mean follow-up period was 60.5 months (range, 4-92 months). Age, sex, tumour stage, tumour thickness and volume, and perineural involvement were not predictive of locoregional recurrence or survival. Pathological tumour stage (T1 vs T2) was a prognostic factor for both five-year overall survival (87.3 vs 65.6 per cent, p = 0.042) and disease-free survival (88.6 vs 65.6 per cent, p = 0.037). Conclusion: Tumour stage was clearly a major factor affecting the prognosis of surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status had been implemented. Copyright © JLO (1984) Limited 2017.
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Adult , Aged , Aged, 80 and over , Disease-Free Survival , Female , Humans , Lip Neoplasms , Male , Middle Aged , Neck , Neck Dissection , Neoplasm Staging , Prognosis , Survival Analysis , Treatment Outcome , age , aged , Article , cancer prognosis , cancer recurrence , cancer size , cancer staging , cancer survival , clinical article , demography , disease free survival , female , follow up , histopathology , human , lip cancer , local recurrence free survival , male , overall survival , perineural invasion , reference value , retrospective study , sex difference , wedge resection , adult , Lip Neoplasms , middle aged , neck , neck dissection , pathology , procedures , prognosis , survival analysis , treatment outcome , very elderly