Risk factors for renal scarring in children with primary vesicoureteral reflux disease.

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dc.contributor.authorMir S.
dc.contributor.authorErtan P.
dc.contributor.authorOzkayin N.
dc.date.accessioned2024-07-22T08:19:06Z
dc.date.available2024-07-22T08:19:06Z
dc.date.issued2013
dc.description.abstractTo determine the incidence of renal scarring among patients with primary vesicoureteral reflux (VUR) and the possible risk factor(s), we studied 90 children (60 girls and 30 boys) with VUR followed in the Pediatric Nephrology Unit at the Ege University Hospital from 1998 to 2003. All the patients were assessed for VUR grade by voiding cystoureterography and for presence of renal scarring by (99 m) technetium dimercapto-succinic acid scintigraphy. All infants with VUR were given low-dose prophylactic antibiotics and followed-up until resolution of the reflux. Grade of reflux and number of urinary tract infection (UTI) episodes (≥3) were found to be statistically significant risk factors for renal scarring (P <0.05). However, gender, familial history and laterality of the disease were not found to be statistically significant risk factors (P >0.05). Similarly, there was no statistically significant difference of frequency of renal scarring among the different age groups (P >0.05). We conclude that recurrences of UTI and VUR severity are significant risk factors for renal scarring in children with VUR. Therefore, identification of VUR at an early age may offer the opportunity to prevent episodes of UTI and possible formation of renal scars that may result in end-stage renal failure.
dc.identifier.DOI-ID10.4103/1319-2442.106241
dc.identifier.issn13192442
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17529
dc.language.isoEnglish
dc.rightsAll Open Access; Gold Open Access
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectCicatrix
dc.subjectDisease Progression
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectIncidence
dc.subjectKidney
dc.subjectKidney Failure, Chronic
dc.subjectMale
dc.subjectRadionuclide Imaging
dc.subjectRetrospective Studies
dc.subjectRisk Factors
dc.subjectSeverity of Illness Index
dc.subjectTurkey
dc.subjectUrination
dc.subjectUrography
dc.subjectVesico-Ureteral Reflux
dc.subjectarticle
dc.subjectchild
dc.subjectchronic kidney failure
dc.subjectcomparative study
dc.subjectdisease course
dc.subjectfemale
dc.subjectfollow up
dc.subjecthuman
dc.subjectincidence
dc.subjectkidney
dc.subjectmale
dc.subjectmethodology
dc.subjectmicturition
dc.subjectpathology
dc.subjectpathophysiology
dc.subjectpreschool child
dc.subjectradiography
dc.subjectretrospective study
dc.subjectrisk factor
dc.subjectscar
dc.subjectscintiscanning
dc.subjectseverity of illness index
dc.subjectTurkey (republic)
dc.subjecturography
dc.subjectvesicoureteral reflux
dc.titleRisk factors for renal scarring in children with primary vesicoureteral reflux disease.
dc.typeArticle

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