Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls
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Date
2016
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Abstract
Objectives: To compare sexual function and hormone profile in male patients with gynecomastia with matched controls. MATERIALS-METHODS: Forty-seven male subjects with gynecomastia and thirty healthy controls were enrolled in this study. Serum free T3, free T4, TSH, FSH, prolactin, estradiol, total testosterone, free testosterone, DHEA-SO4, LH and total PSA were measured in the patients and controls. Sexual function of the patients and controls were evaluated using International Index of Erectile Function (IIEF). The hormone values and IIEF scores of the patients were statistically compared with the controls'. RESULTS: The mean of age, body mass index, right and left testicular volume in the patient and control group were similar. The mean FSH and free T3 values of the patients were significantly lower than the controls (p = 0:007 and p = 0:03, respectively). The mean of the other hormone values in the both groups were found to be statistically similar (p > 0:05). The mean ±SD of total IIEF scores in the patient and control group were 60:14 ± 8:78 and 65:24 ± 5:52, respectively (p = 0:007). Although the mean IIEF-erectile function, orgasmic function and intercourse satisfaction scores in the patient group were significantly lower than the control group (p < 0:001, p = 0:004 and p = 0:001, respectively), the mean IIEF-desire score of the patients was significantly higher than the controls (p = 0:002). CONCLUSION: We found that the hormone profiles (except FSH and free T3) of the patients with gynecomastia were similar with the controls. However, gynecomastia adversely affected male sexual function. © 2016-IOS Press and the authors. All rights reserved.
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Adolescent , Adult , Case-Control Studies , Dehydroepiandrosterone Sulfate , Erectile Dysfunction , Estradiol , Follicle Stimulating Hormone , Gynecomastia , Humans , Kallikreins , Luteinizing Hormone , Male , Orgasm , Penile Erection , Prolactin , Prostate-Specific Antigen , Reproductive Health , Sexual Dysfunctions, Psychological , Testosterone , Thyrotropin , Thyroxine , Triiodothyronine , Young Adult , estradiol , follitropin , luteinizing hormone , prolactin , testosterone , thyrotropin , estradiol , follitropin , kallikrein , kallikrein-related peptidase 3, human , liothyronine , luteinizing hormone , prasterone sulfate , prolactin , prostate specific antigen , testosterone , thyrotropin , thyroxine , adult , Article , body mass , clinical article , controlled study , estradiol blood level , follitropin blood level , gynecomastia , hormone response , human , International Index of Erectile Function , luteinizing hormone blood level , male , middle aged , priority journal , prolactin blood level , sexual behavior , sexual function , sexual intercourse , sexual satisfaction , testis size , testosterone blood level , adolescent , blood , case control study , erectile dysfunction , gynecomastia , orgasm , penis erection , reproductive health , Sexual Dysfunctions, Psychological , young adult