Primary pleural synovial sarcoma with diffuse pleural involvement: A case report; [Sarcome synovial pleural primitif avec atteinte pleurale diffuse : un rapport de cas]
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Date
2023
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Abstract
Synovial sarcoma (SS) is a mesenchymal tumor which generally affects the soft tissues of the extremities. Primary pleural synovial sarcoma (PPSS) is a very rare and aggressive subtype of SS. A 73-year-old male patient presented with chest-back pain and dyspnea. Hypermetabolic diffuse pleural lesions were detected in 18F-FDG PET/CT performed after pleural nodular thickenings were observed on CT. As the result of the molecular analysis performed in the excisional biopsy, SYT-SSX mutation was detected and the patient was diagnosed as SS. Pazopanib treatment was commenced. We are reporting a very rare case of PPSS with diffuse pleural involvement. © 2023 Elsevier Masson SAS
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Keywords
fluorodeoxyglucose f 18 , oncogene fusion protein , pazopanib , syt ssx fusion protein , tumor marker , unclassified drug , aged , Article , backache , cancer chemotherapy , cancer morphology , case report , clinical article , computer assisted tomography , dyspnea , emergency ward , excisional biopsy , exudative pleural effusion , fine needle aspiration biopsy , fluorescence in situ hybridization , follow up , gene mutation , histopathology , human , human tissue , hypermetabolism , male , maximum standardized uptake value , mediastinum lymph node , molecular diagnosis , molecular genetics , mutational analysis , pleura effusion , pleura mesothelioma , pleura thickening , pleural sarcoma , positron emission tomography-computed tomography , primary pleural synovial sarcoma , primary tumor , respiratory distress , synovial sarcoma , thorax drainage , thorax pain , thorax radiography , transthoracic aspiration , transthoracic biopsy , treatment response , tumor biopsy , video assisted thoracoscopic surgery