Neonatal Cholestasis as Initial Presentation of Portosystemic Shunt: A Case Report

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dc.contributor.authorDoğan G.
dc.contributor.authorDüzgün F.
dc.contributor.authorTarhan S.
dc.contributor.authorAppak Y.Ç.
dc.contributor.authorKasırga E.
dc.date.accessioned2024-07-22T08:11:20Z
dc.date.available2024-07-22T08:11:20Z
dc.date.issued2016
dc.description.abstractCongenital intrahepatic portosystemic shunts are rare in children. Portosystemic venous malformations are characterized by extreme clinical variability. We report a full-term 33-day-old male infant presenting with neonatal jaundice. On physical examination, he had generalized icterus and the liver was palpable 3.5 cm below the right costal margin. He had no other symptoms. Laboratory tests showed AST 632 U/L, ALT 198 U/L, total bilirubin 12.1 mg/dL, conjugated bilirubin 10.2 mg/dL, alkaline phosphatase 753 U/L, GGT 47 U/L and glucose 67 U/L. Colour Doppler ultrasonography showed the left portal vein was more dilated than the right portal branch and communication with dilated left hepatic vein. There was no evidence of portal hypertension, heart failure, hepatopulmonary syndrome and encephalopathy during his hospital stay, so he was discharged from the pediatric department and his parents advised to attend monthly follow-up. Congenital portosystemic shunts are rarely observed in the childhood period.1 Depending on anatomic characteristics they may be intrahepatic or extrahepatic.2 Intrahepatic portosystemic shunts (PSS) are observed between the portal vein and hepatic vein or vena cava inferior.3,4 Small shunts may close themselves before the age of 2 years.5 With the increase in use of imaging methods, diagnosing PSS has become easier, with an increase in the number of cases reported.6 Neonatal cholestatis is a frequent complication of PSS.1 We present a case presenting with neonatal cholestasis diagnosed with congenital intrahepatic PSS. © 2016
dc.identifier.DOI-ID10.1016/j.jceh.2016.08.007
dc.identifier.issn09736883
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15613
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.rightsAll Open Access; Green Open Access
dc.subjectalanine aminotransferase
dc.subjectalkaline phosphatase
dc.subjectaspartate aminotransferase
dc.subjectbilirubin glucuronide
dc.subjectglucose
dc.subjectthyrotropin
dc.subjectursodeoxycholic acid
dc.subjectArticle
dc.subjectbrain disease
dc.subjectcase report
dc.subjectcholestasis
dc.subjectDoppler ultrasonography
dc.subjectechocardiography
dc.subjectfeces analysis
dc.subjectfeces color
dc.subjectfollow up
dc.subjectheart failure
dc.subjecthepatomegaly
dc.subjecthepatopulmonary syndrome
dc.subjecthospital discharge
dc.subjecthospitalization
dc.subjecthuman
dc.subjectinfant
dc.subjectliver vein
dc.subjectmale
dc.subjectneurologic examination
dc.subjectnewborn jaundice
dc.subjectphysical examination
dc.subjectportal hypertension
dc.subjectportal vein
dc.subjectportosystemic anastomosis
dc.subjectpriority journal
dc.subjectvein dilatation
dc.titleNeonatal Cholestasis as Initial Presentation of Portosystemic Shunt: A Case Report
dc.typeArticle

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